Topical microemulsion of capsaicin without surfactant was developed in this study. In these systems, the oil phase was benzyl alcohol, and the cosurfactant was propylene glycol and ethanol. The drop-size of the systems was measured by dynamic light scattering method in order to distinguish true solution from microemulsion. The transdermal performance of the microemulsions was evaluated in vitro...

A lot of researches have investigated the effects of topical cyclosporine A on the eye surface layers’ diseases. By now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. The aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. To reach higher corneal dru...

Microemulsions are the advanced form of conventionally used emulsions, which is a biphasic dosage consisting two immiscible liquids that brought together with application surfactants and cosurfactants. The micron sized globules microemulsions helps in achieving targeted action improved availability stability. studies related to concluded its potential delivering various hydrophilic lipophilic d...

PURPOSE In the present study, histological aspects were considered in order to evaluate the in vivo photoprotective effect of a w/o microemulsion containing quercetin against UVB irradiation-induced dermal damages. The toxicity in cell culture and the potential skin irritation resulting from topical application of this formulation were also investigated. METHODS Mouse dorsal surfaces were tre...