Introduction Toltrazuril (Tol) is used to prevent and combat coccidiosis. However, its low aqueous solubility and poor oral bioavailability limit clinical application. Methods To overcome the shortcomings, toltrazuril-hydroxypropyl-β-cyclodextrin inclusion complex (Tol-HP-β-CD) was prepared and characterized. The comparative plasma disposition kinetics of Tol was analyzed after a single orall...

1 Wheat Research Center, Bangladesh Agricultural Research Institute, Gazipur, Bangladesh ABSTRACT. Twenty five spring wheat genotypes were evaluated for terminal heat stress tolerance in field environments in the Agro Ecological Zone-11 of Bangladesh, during 2009-2010 cropping season. The experiments were conducted at Wheat Research Centre, Bangladesh Agricultural Research Institute, using rand...

The mating-type locus in the haploid filamentous fungus, Neurospora crassa, controls mating and sexual development. The fusion of reproductive structures of opposite mating type, A and a, is required to initiate sexual reproduction. However, the fusion of hyphae of opposite mating type during vegetative growth results in growth inhibition and cell death, a process that is mediated by the tol lo...

Some plasmid-free Tol- strains derived from Pseudomonas putida PAW1 (which carries the TOL plasmid pWW0) have a segment of TOL DNA located chromosomally. Of three independently isolated strains, PAW86 had an integrated TOL segment of 16 kilobases and PAW85 had two copies of this segment in different chromosomal locations, whereas the chromosomal DNA of PAW82 showed no homology with the TOL plas...

abstract: evaluation of drought tolerance for 20 barley genotypes were conducted under normal irrigation and terminal stress condition by withholding irrigation at the time of 50% flowering. drought effect on grain yield and plant total mass traits was studied and eight of stress indices including stress tolerance index (sti), stress tolerance (tol), stress susceptibility index (ssi), mean prod...

Plants of six wheat varieties (Damani, Hashim-8, Gomal-8, DN-73, Zam-04, and Dera-98) were grown under three water regimes i.e. 100% Field Capacity (FC), 35% FC and 25% FC. Results of this experiment showed highly significant difference among wheat varieties in all the studied traits and water stress conditions decreased them significantly. The superior variety Hashim-8 which indicated higher r...

This paper describes the use of an a posteriori error estimator to control anisotropic mesh adaptation for computing inviscid compressible flows. The a posteriori error estimator and the coupling strategy with an anisotropic remesher are first introduced. The mesh adaptation is controlled by a single-parameter tolerance (TOL) in regions where the solution is regular, whereas a condition on the ...

IFN-gamma has been shown to inhibit monocyte (Mo) differentiation into mature dendritic cells (DC). Because IFN-gamma also plays a role in tolerance induction, we asked whether this could be related to generation of tolerogenic DC (Tol-DC). Toward this aim, we cultured Mo with GM-CSF plus IL-4 in the presence or absence of IFN-gamma for 6 days and induced their maturation with TNF-alpha for 2 a...

We present VLT spectroscopic observations with different spectral resolutions and different slit orientations of the two metal-deficient blue compact dwarf (BCD) galaxies Tol 1214–277 and Tol 65. The oxygen abundances in the brightest H ii regions of Tol 1214–277 and Tol 65 are found to be 12 + log O/H = 7.55 ± 0.01 and 7.54 ± 0.01, or Z⊙/24 . The nitrogen-to-oxygen abundance ratios in the two ...