T lymphocyte subset percentages were determined in 16 total lymphoid irradiation (TLI) treated and 18 sham treated control patients with chronic progressive multiple sclerosis. During the first year after treatment, the ratio of T helper/inducer to T suppressor/cytotoxic cells (Th/Ts ratio) was significantly higher in sham treated multiple sclerosis patients who worsened clinically compared wit...

Lewis rats given total lymphoid irradiation (TLI) accepted bone marrow allografts from AgB-incompatible donors. The chimeras showed no clinical signs of graft-versus-host disease. Skin allografts from the marrow donor strain survived for more than 150 days on the chimeras. However, third-party skin grafts were rejected promptly. Although heart allografts survived more than 300 days in Lewis rec...

This study evaluated the sensitivity of maximum likelihood (ML)-, generalized least squares (GLS)-, and asymptotic distribution-free (ADF)-based fit indices to model misspecification, under conditions that varied sample size and distribution. The effect of violating assumptions of asymptotic robustness theory also was examined. Standardized root-mean-square residual (SRMR) was the most sensitiv...

PURPOSE To retrospectively evaluate the outcome and toxicity of total lymphoid irradiation (TLI) based conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in severe aplastic anemia (SAA) patients who experienced an engraftment failure from prior HSCT or were heavily transfused. MATERIALS AND METHODS Between 1995 and 2006, 20 SAA patients received TLI for conditi...

The CALO desktop assistant aims to provide assistance through many AI technologies, including several techniques for learning to perform tasks. Based on our experiences implementing Tailor, a tool for task learning by instruction (TLI) in Calo, we explore the requirements for integrating TLI more closely into the assistant. The benefits of integration include a more coherent user experience and...

N-Nitroso-N-methylurea (NMU) is an effective carcinogen for the induction of mammary carcinoma in the rat. Tamoxifen (TAM), used as a chemopreventive agent to reduce tumor incidence, has been well studied using this model. We have utilized the rat mammary carcinoma model to assess the effect of TAM on preneoplastic changes. Fifty-day-old virgin female Sprague-Dawley rats were randomized by weig...

BACKGROUND Mental workload assessment is a recurrent issue in air traffic control (ATC). Studies of ATC have used either objective aspects, i.e., numbers and distribution of aircraft, or subjective factors, such as self-imposed performance and stress levels, with mixed results. This is partly due to the difficulty in bringing together comparable data pertaining to both air traffic, with its eve...

The thymidine labeling index (TLI) showed a lognormal distribution for 133 primary breast carcinomas with a median of 2.21 and a range of 0.04 to 18.6/100. High TLI's were associated significantly with nuclear anaplasia, pushing tumor border, necrosis, cellular inflammation, and total replacement of lymph nodes involved by tumor, and the data suggested an association of high TLI with large prim...

OBJECTIVE The present study aimed to undertake a review of available evidence assessing whether time-lapse imaging (TLI) has favorable outcomes for embryo incubation and selection compared with conventional methods in clinical in vitro fertilization (IVF). METHODS Using PubMed, EMBASE, Cochrane library and ClinicalTrial.gov up to February 2017 to search for randomized controlled trials (RCTs)...

BACKGROUND A proportion of heart transplant recipients develop poor graft function in the absence of cellular infiltrate in endomyocardial biopsies or transplant associated coronary artery disease. The condition has a poor prognosis and its aetiology is poorly understood. We report encouraging intermediate term results with total lymphoid irradiation (TLI) in the management of this condition. ...