OBJECTIVE This study was to evaluate the efficacy of the hyaluronic acid (HA) bioabsorbable membrane combined use with both expanded-polytetrafluoroethylene (ePTFE) and autologous pericardium for preventing postoperative pericardial adhesions. METHODS The HA bioresorbable surgical membrane (Seprafilm, Genzyme, Cambridge, Mass) was used with either ePTFE or autologous pericardium in an experim...

BACKGROUND After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions. METHODS Eight beagles were divided into an experimental group (five males) and a control group (three females). The experimental group underwent thoracotomy on both ...

BACKGROUND Postoperative intra-abdominal adhesions are common complications after abdominal surgery. The exact molecular mechanisms that are responsible for these complications remain unclear, and there are no effective methods for preventing adhesion formation or reformation. The aim of the study reported here was to investigate the preventive effects and underlying potential molecular mechani...

to determine the prevalence of asherman's syndrome in the south of iran and assess the safety and efficacy of hysteroscopic adhesiolysis in restoration of menstrual function and fertility, a prospective study was done from 1997 to 1999. among 2300 couples with infertility referring to the infertility clinic of a shiraz university hospital, 30 patients were proven to have asherman's sy...

Postoperative adhesions represent a common consequence in patients who underwent abdominal or pelvic surgery. Such adhesions can be asymptomatic, but they can cause complications such as chronic abdomino-pelvic pain, secondary infertility, an increase in bowel obstruction risk and more complexity for future surgery, including longer surgery times and an increase in morbidity. Normally, adhesion...

The adhesion of cells to the extracellular matrix is a dynamic process, mediated by a series of cell-surface and matrix-associated molecules that interact with each other in a spatially and temporally regulated manner. These interactions play a major role in tissue formation, cellular migration and the induction of adhesion-mediated transmembrane signals. In this paper, we show that the formati...

Cell-matrix adhesions are large, multimolecular complexes through which cells sense and respond to their environment. They also mediate migration by serving as traction points and signaling centers and allow the cell to modify the surroucnding tissue. Due to their fundamental role in cell behavior, adhesions are germane to nearly all major human health pathologies. However, adhesions are extrem...

Objective to identify the impact of adhesions related to endometriosis on quality of life among infertile women. MaterialsAndMethods Cross-sectional, correlational study design was used. The study was performed at Endoscopic Unit, in Zagazig University Hospitals, Egypt. Oral consent to participate in this study was taken from 109 women who were candidates for laparoscopy as infertile cases and ...

Tendon reconstruction using grafts often results in adhesions that limit joint flexion. These adhesions are precipitated by inflammation, fibrosis, and the paucity of tendon differentiation signals during healing. In order to study this problem, we developed a mouse model in which the flexor digitorum longus (FDL) tendon is reconstructed using a live autograft or a freeze-dried allograft, and i...