We are investigating the evolution of four big US stock market indexes' regular returns after 2000 technology crash and 2007-2009 financial crisis. Our approach is based on topological data processing (TDA). To identify measure phenomena occurring in multidimensional time series, we use persistence homology. obtain time-dependent point cloud sets using a sliding window, which connect space for....

Laboratory based gait analysis techniques are expensive, time consuming and require technical expertise. Inertial measurement units can directly measure temporal parameters and in combination with gait models may provide a solution to obtain spatial gait measurements within daily clinical assessments. However it is not known if a model and standard correction factor determined by Zijlstra and H...

We are interested in evaluating the state of drivers to determine whether they attentive road or not by using motion sensor data collected from car driving experiments. That is, our goal is design a predictive model that can estimate given sensors. For purpose, we leverage recent developments topological analysis (TDA) analyze and transform coming time series build machine learning based on fea...

This paper describes a localized algorithm for the topological simplification of scalar data, an essential pre-processing step data analysis (TDA). Given field f and selection extrema to preserve, proposed (LTS) derives function g that is close only exhibits selected set extrema. Specifically, suband superlevel components associated with undesired are first locally flattened then correctly embe...

The prevalence of cervical disc disease is high, and the traditional surgical method of anterior cervical discectomy and fusion (ACDF) carries with it the disadvantages of motion loss at the operated level, and accelerated adjacent level disc degeneration. Preliminary results of the efficacy and reoperative rate comparing TDA versus ACDF have been reported; however, the long-term outcomes of TD...

The objective of this matched case-control study was to determine whether women with Même or Replicon polyurethane-covered silicone breast implants are exposed to clinically significant levels of free 2,4-TDA from biodegradation of the polyurethane foam. Urine and serum samples were obtained from 61 patients with Même or Replicon breast implants and 61 controls on two separate occasions separat...

1,2-Dibromoethane (1,2-DBE) is a carcinogenic compound that is metabolized both by cytochrome P450 (P450) and glutathione S-transferase (GST) enzymes, and that has been used by us as a model compound to study interindividual variability in biotransformation reactions. In this study, the excretion of thiodiacetic acid (TDA) and S-(2-hydroxyethyl)-N-acetyl-l-cysteine (2-HEMA) were measured in the...

Three new thiodiacetato-Cu(II) chelates have been synthesized and studied by X-ray crystallography and by thermal, spectral and magnetic methods. [Cu(tda)]n (1) is a 3D-polymer with a pentadentate tda, which acts with a fac-O2 + S(apical)-tridentate chelating conformation and as a twofold anti, syn-l–g:g carboxylate bridge. In its square pyramidal Cu(II) coordination (type 4 + 1) four O(carboxy...

OBJECTIVE To develop and validate a predictive model to estimate the probability of being nonadherent to topical glaucoma medications. DESIGN Prospective cohort study. PARTICIPANTS Patients being treated with once-daily prostaglandin eye drops. METHODS A predictive model for nonadherence was developed from the Travatan Dosing Aid (TDA) study (n = 196) using stepwise logistic regression. T...

Surface-associated marine bacteria often produce secondary metabolites with antagonistic activities. In this study, tropodithietic acid (TDA) was identified to be responsible for the antibacterial activity of the marine epiphytic bacterium Pseudovibrio sp. D323 and related strains. Phenol was also produced by these bacteria but was not directly related to the antibacterial activity. TDA was sho...