The management of acute myocardial infarction (AMI) was altered dramatically with the introduction of intracoronary thrombolytic therapy in the late l970s by Rentrop and others.1 The visualization of coronary artery occlusion by angiography performed during the first few hours of AMI and the removal of some of these thrombi at the time of emergent coronary artery bypass surgery convinced the me...

Current mainstay treatment for pulmonary embolism (PE) includes oral anticoagulation, thrombolytic therapy, catheter embolectomy and acute surgical embolectomy. Surgical embolectomy is reserved for hemodynamically unstable patients (cardiogenic shock, cardiac arrest) and contraindication to thrombolytic therapy. We report a case of saddle PE in a young female with echocardiographic signs of rig...

BACKGROUND Dysfunction after thrombolytic therapy of acute myocardial infarction (MI) may be reversible. Early after myocardial infarction, both reversible and irreversible injury may be manifested by regional wall motion abnormalities. Improved wall thickening during dobutamine infusion (dobutamine-responsive wall motion) may accurately identify reversibly injured segments. METHODS AND RESUL...

IN 1-2% of patients with deep vein thrombosis (DVT), pulmonary emboli develop despite therapy with heparin.' Episodes of DVT successfully treated with anticoagulant therapy may still result in venous valvular incompetence and lead to postphlebitic syndromes characterized by ulceration, varicosities and edema. Studies of thrombolytic agents suggest that early use of these drugs for extensive ven...

background: the use of thrombolytic agents in the treatment of hemodynamically stable patients with acute submassive pulmonary embolism (pte) remains controversial. we, therefore, conducted this study to compare the effect of thrombolytic plus anticoagulation versus anticoagulation alone on early death and adverse outcome following submassive pte. methods: w e conducted a study of patients with...

background: thrombolytic therapy is the only approved treatment for acute cerebral ischemia. the hemorrhagic transformation is the greatest complication of this treatment, which may occur after recanalization of occluded artery. the aim of this study was to determine factors associated with clinical improvement and worsening in patients with acute ischemic stroke treated with intravenous thromb...

BACKGROUND Prosthetic heart valve thrombosis is a life-threatening condition for which treatment has not been evaluated by randomized trials. OBJECTIVES To compare surgery with thrombolytic therapy for the treatment of prosthetic valve thrombosis. METHODS A comprehensive systematic review was carried out by independent researchers using PubMed, Web of Knowledge, HINARI, LILACS and EMBASE, i...

Spinal cord injures are associated with a high incidence of deep vein thrombosis (DVT), and, in consequence, associated also with a greater frequency of pulmonary emboli (PE), reported in the literature to occur in 70 to 100% of those cases . The extent of the pulmonar vascular obstruction is probably the most important determinant of the right ventricular dysfunction, which in turn leeds to wo...

a 45- year old man with a history of aortic valve replacement presented with acute chest pain which was diagnosed to be anterior wall myocardial infarction. he received thrombolytic therapy with streptokinase. echocardiography and fluoroscopy showed normally functioning ball and cage aortic prosthesis. coronary arteriography showed globular filling defect in midportion of left anterior descendi...