We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofunction in experimental acute lung injury (ALI). Thirty-six Wistar rats were randomly divided into five groups. Control (C) and ALI animals received sterile saline solution and Escherichia coli lipopolysaccharide by intraperitoneal injection respectively. After 24h...

Background: Electroconvulsive therapy (ECT) is an effective treatment in major depressive disorder (MDD). Earlier studies suggest that ketamine has antidepressive effects and prolongs seizure duration in favor of therapeutic efficacy of ECT. A great concern with the use of ketamine is its possible adverse hemodynamic effects during ECT. This study was conducted to compare the hemodynamic effect...

Veterinary professionals are still looking for a suitable method of euthanasia that causes an easy death animals with minimum pain, fear, and suffering. The present study describes in rescued horses using xylazine hydrochloride thiopental sodium. was conducted at Teaching Hospital, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Bangladesh. Xylazine (0.1 mg/kg; 20mg/ml) sodium (10 25...

BACKGROUND Bronchospasm is a potential complication in anyone undergoing general anesthesia. Because volatile anesthetics relax bronchial smooth muscle, the effects of two newer volatile anesthetics, desflurane and sevoflurane, on respiratory resistance were evaluated. The authors hypothesized that desflurane would have greater bronchodilating effects because of its ability to increase sympathe...

UNLABELLED We compared two conventional induction techniques (thiopental and propofol), an inhaled induction with sevoflurane using a circle system, and a rebreathing method. Fentanyl 1 microg/kg was given to women undergoing 10- to 20-min procedures. Anesthesia was induced (n = 20 each) with one of the following: 1) sevoflurane and N2O from a rebreathing bag (Sevo/Bag). A 5-L bag was prefilled...

to determine the neuropharmacological activity of the leaf extract of croton zambesicus in mice and chicks. the effect of aqueous leaf extract of croton zambesicus on thiopental sodium – induced sleeping time in mice, on gross locomotor activity (gla) in 2-day old chicks and effect of extract on apomorphine - induced stereotyped behavior in chicks were evaluated. the aqueous extract (1000 and 1...

Much ~ been written m recent years of the relative advantages and chsadvantages of new intravenous anaesthetics. Such comparisons are always difficult to make because of the many variables which ca~Lnot be easily controlled in a clinical series. For that reason, we attempted some time ago to compare a number of intravenous agents in human vol~mteers, a&a~inistering each drug consecutively to th...

Sodium pentobarbital and sodium thiopental decrease both the peak initial (Na) and late steady-state (K) currents and reduce the maximum sodium and potassium conductance increases in voltage-clamped lobster giant axons. These barbiturates also slow the rate at which the sodium conductance turns on, and shift the normalized sodium conductance vs. voltage curves in the direction of depolarization...