We report here a case of adult-onset Still's disease (AOSD), who finally responded to a combination of cyclophosphamide (CPA) and gold sodium thiomalate (GST) after two years of active disease. A 23-year-old man having continuous high fever with skin rash, polyarthralgia and increased serum ferritin, was diagnosed as AOSD, and oral corticosteroid was initially effective. His symptoms recurred o...

A patient with seropositive, nodular rheumatoid arthritis (RA) developed contact allergy to gold jewellery following a severe skin rash which occurred after 13 weeks of treatment with sodium aurothiomalate. Patch testing confirmed that the contact allergy was due to gold. This is the first proved case of contact allergy to gold or any other compound initiated by systemic administration of the a...

Life-table analysis was applied to the records of 317 patients with rheumatoid arthritis (RA) treated with sulphasalazine (SAS), 201 treated with sodium aurothiomalate (gold), and 163 with penicillamine. They comprised all those treated in our department with these drugs between January 1973 and July 1984. Risks of treatment termination for all reasons were similar for each drug at five years (...

The efficient recruitment of physicians “specially qualified” in the principles of “modern tropical medicine and hygiene” proved, however, to be a difficult task. To address this problem, the Secretary of State for the Colonies, Joseph Chamberlain, organized a committee in 1901 to draw up plans for amalgamating the six medical departments of British West Africa. Their primary goal was to devise...

The author describes this small book as a ' paper' and this is a more or less correct definition because it is by no means a finished presentation of the subject. It is composed of two parts. Part I is devoted to a brief description of the general physical characters of certain tribes in the Gold Coast and the diets they consume. This is necessarily incomplete as proper analysis of the various ...