Administration of thioacetamide to rats for 4 days has been shown previously to increase the activity of liver messenger RNA (mRNA) and to disproportionately increase the activity of albumin mRNA in the wheat germ translation system. We have explored the possibility that administration of thioacetamide quantitatively alters the transcription of rat liver unique DNA. Nucleic acid hybridization b...

Background & Aim: Acute liver damage, inflammation and oxidative stress are underlying tissue necrosis and development of ciroces. The aim of this study was to evaluate the effect of Satureja bakhtiarica extract on acute liver disease induced by the thioacetamide and TNF-α and IL-6 cytokines level.  Experimental: In experimental study, 36 Wistar ...

in this investigation, we report facile synthesis of cadmium(ii)-thioacetamide nanocomposites in the presence and absence of polyvinyl alcohol under ultrasonic irradiations, using cadmium acetate dihydrate (cd(ch3coo)2.2h2o), potassium iodide (ki), thioacetamide (taa, ch3csnh2), and polyvinyl alcohol (pva) as the starting materials. results show that in the presence of polyvinyl alcohol size...

In this investigation, we report facile synthesis of cadmium(II)-thioacetamide nanocomposites in the presence and absence of polyvinyl alcohol under ultrasonic irradiations, using cadmium acetate dihydrate (Cd(CH3COO)2.2H2O), potassium iodide (KI), thioacetamide (TAA, CH3CSNH2), and polyvinyl alcohol (PVA) as the starting materials. Results show that in the presence of polyvinyl alcohol size...

The acid-soluble nuclear proteins of regenerating and thioacetamide-treated rat livers as well as the Morris 9618A hepatoma and the Walker 256 carcinosarcoma were ex tracted from citric acid-isolated nuclei with 0.4 N H2SO4. The nuclear extracts were analyzed by two-dimensional polyacrylamide gel electrophoresis. Although most of the protein spots were common to the livers and tumors stud ied, ...

The aim of the present study was to evaluate the protective activity of aqueous extract from Platycodon grandiflorum (BC703) on thioacetamide (TA)-induced hepatotoxicity in mice. We found that BC703 significantly decreased mortality and the change in serum transaminase following TA administration. The group treated with BC703 at doses of 1, 5, and 10 mg/kg produced significant hepatoprotective ...

The acid-soluble nuclear proteins of regenerating and thioacetamide-treated rat livers as well as the Morris 9618A hepatoma and the Walker 256 carcinosarcoma were ex tracted from citric acid-isolated nuclei with 0.4 N H2SO4. The nuclear extracts were analyzed by two-dimensional polyacrylamide gel electrophoresis. Although most of the protein spots were common to the livers and tumors stud ied, ...