We propose a material point method (MPM) to model the evolving multi-body contacts due crack growth and fragmentation of thermo-elastic bodies. By representing particle interface with an implicit function, we adopt gradient partition techniques introduced by Homel Herbold (2017) identify separation between pair distinct surfaces. This treatment allows us replicate frictional heating interfaces ...

Purpose – The purpose of this paper is to access performance of existing computational techniques to model strongly non-linear coupled thermo-electric problems. Design/methodology/approach – A thermistor is studied as an example of a strongly non-linear diffusion problem. The temperature field and the current flow in the device are mutually coupled via ohmic heating and very rapid variations of...

A general framework for the thermodynamics of open systems is presented. The theory is fundamentally based on the generalized balance of mass, which is enhanced by additional surface-°ux and volume-source terms. The presentation highlights the in°uence of the enhanced mass balance on the remaining balance equations. To clarify the impact of the variable reference density, we introduce the notio...

formulation by using chemical penetration enhancers and to study the effect of pulsed current on permeation through guinea pig, Wistar rat and human cadaver skin. Modified Franz diffusion cell was used to study the in vitro permeation across various types of skin by iontophoresis. The thermo-reversible gel was prepared and optimized by cold method using poloxamer 407 as a gelling agent. Thermo-...

Magnetic nanocarriers have attracted increasing attention for multimodal cancer therapy due to the possibility to deliver heat and drugs locally. The present study reports the development of magnetic nanocomposites (MNCs) made of an iron oxide core and a pH- and thermo-responsive polymer shell, that can be used as both hyperthermic agent and drug carrier. The conjugation of anticancer drug doxo...