This paper proposes an aggregation-based model reduction method for nonlinear models of multi-zone building thermal dynamics. The full-order model, which is already a lumped-parameter approximation, quickly grows in state space dimension as the number of zones increases. An advantage of the proposed method, apart from being applicable to the nonlinear thermal models, is that the reduced model o...

Using effective medium theory the authors demonstrate that the thermal conductivity of nanofluids can be significantly enhanced by the aggregation of nanoparticles into clusters. Predictions of the effective medium theory are in excellent agreement with detailed numerical calculation on model nanofluids involving fractal clusters and show the importance of cluster morphology on thermal conducti...

Our studies investigated functional interactions between calreticulin, an endoplasmic reticulum chaperone, and major histocompatibility complex (MHC) class I molecules. Using in vitro thermal aggregation assays, we established that calreticulin can inhibit heat-induced aggregation of soluble, peptide-deficient HLA-A2 purified from supernatants of insect cells. The presence of HLA-A2-specific pe...

We present a study of the dyna aggregation using a common path heterodyn wave label-free sensing scheme. We demonstr detect, during thermal incubation, the first events of protein aggregation and fibrillogen beta peptides, linked to Alzheimer’s Disease. T the biosensor is made using Lysozyme protein protein model system to examine structural principles. The sensor is able to detect the for solu...

A general kinetic model based on accurate density-functional-theoretic total-energy calculations is introduced to describe the aggregation kinetics of oxygen-related thermal double donors (TDD's) in silicon. The calculated kinetics, which incorporates the reactions of associations, dissociations, and isomerizations of all relevant oxygen complexes, is in agreement with experimental annealing st...