Deep brain stimulation (DBS) has been established as an effective treatment for Parkinson’s disease and other movement disorders. The stimulation is currently administered using tetrode-macroelectrodes that target the subthalamic nucleus (STN). This often leads to side effects which bias the surrounding areas, e.g. the speech centre. Targeting a specific brain region can better be achieved with...

In the Large Helical Device (LHD), the installation of a pair of ion cyclotron range of frequencies (ICRF) antennas from upper and lower ports is planned. These antennas are geometrically symmetrical and located side by side. By changing the current phase on the straps, the wave number parallel to the magnetic field line can be controlled. However, antenna impedances will also be changed and re...

Behaviors are generated from complex interactions among networks of neurons. Single-unit ensemble recording has been used to identify multiple neurons in functioning networks. These recordings have provided insight into interactions among neurons in local and distributed circuits. Recorded units in these ensembles have been classed based on waveform type, firing pattern, and physical location. ...

The complex anatomical structure of the central nucleus of the inferior colliculus (ICC), the principal auditory nucleus in the midbrain, may provide the basis for functional organization of auditory information. To investigate this organization, we used tetrodes to record from neighboring neurons in the ICC of anesthetized cats and studied the similarity and difference among the responses of t...

Granule cells in the dentate gyrus of the hippocampus are thought to be essential to memory function by decorrelating overlapping input patterns (pattern separation). A second excitatory cell type in the dentate gyrus, the mossy cell, forms an intricate circuit with granule cells, CA3c pyramidal cells, and local interneurons, but the influence of mossy cells on dentate function is often overloo...

A parallel electrostatic Poisson’s equation solver coupled with parallel adaptive mesh refinement (PAMR) is developed in this paper. The three-dimensional Poisson’s equation is discretized using the Galerkin finite element method using a tetrahedral mesh. The resulting matrix equation is then solved through the parallel conjugate gradient method using the non-overlapping subdomain-by-subdomain ...

The Shockley-Queisser analysis provides a theoretical limit for the maximum energy conversion efficiency of single junction photovoltaic cells. But besides the semiconductor bandgap no other semiconductor properties are considered in the analysis. Here, we show that the maximum conversion efficiency is limited further by the excited state entropy of the semiconductors. The entropy loss can be e...

The cerebellum controls complex, coordinated, and rapid movements, a function requiring precise timing abilities. However, the network mechanisms that underlie the temporal organization of activity in the cerebellum are largely unexplored, because in vivo recordings have usually targeted single units. Here, we use tetrode and multisite recordings to demonstrate that Purkinje cell activity is sy...

Until recently fabrication techniques of Renaissance bronzes have been studied only with the naked eye, microscopically, videoscopically and with X-radiography. These techniques provide information on production techniques, yet much important detail remains unclear. As part of an interdisciplinary study of Renaissance bronzes undertaken by the Rijksmuseum Amsterdam, neutron-imaging techniques h...