Cyclopentolate is widely used in ophthalmology for its intense mydriatic and cycloplegic activity. Systemic side effects have been described in both adults and children. Myoclonic seizure is a rare side effect of eye drops that are used in eye examinations. We report herein a case of convulsion in a three month- old girl following cyclopentolate hydrochloride and phenylephrine hydrochloride eye...

OBJECTIVES To study acute exposure to imidazoline derivatives in 72 children younger than 15 years of age, followed-up from January 1994 to December 1999. METHODS This is a retrospective study of 72 patients with age between 2 months and 13 years (median 2 years; 25-75% = 1 to 3 years old) exposed to naphazoline (N = 48), fenoxazoline (N = 18), oxymetazoline (N = 5) and tetrahydrozoline (N = ...

PURPOSE To evaluate the change of residual volume of eye drop after instillation in patients with 23-gauge microincision vitrectomy surgery (MIVS). METHODS Patient who were treated 23-gauge MIVS from November 2014 to July 2015 were included. The residual volume was defined as the amount of remnant eye drop in patient's eyes after instillation, calculated as the difference between instillation...

Membrane selective electrodes were used to determine tetryzoline hydrochloride (TZH) in pure form, pharmaceutical preparations and in biological fluids. The membrane selective electrodes include construction of water insoluble ion-association complexes. The TZH ion exchangers were formed using tetraphenyl borate (TZH-TPB), phosphomolybdic acid (TZH-PMA) and phosphotungstic acid (TZH-PTA), in a ...

OBJECTIVE To describe the frequency and characteristics of antibiotic prescribing for different types of contacts with the Danish out-of-hours (OOH) primary care service. DESIGN Population-based observational registry study using routine registry data from the OOH registration system on patient contacts and ATC-coded prescriptions. SETTING The OOH primary care service in the Central Denmark...

The cyclic AMP-dependent protein kinase (isoenzymes I and II) was measured using a synthetic peptide analog of the porcine hepatic phosphorylation site sequence (Leu-Arg-Arg-Ala-Ser-&eu-Gly). Epinephrine caused a timeand dose-dependent activation of the hepatic cyclic AMP-dependent protein kinase and inactivation of pyruvate kinase. Maximal activation of the protein kinase occurred within 1 min...

PURPOSE To evaluate the effectiveness and safety of 0.3% sodium hyaluronate (HA) compared to recombinant bovine basic fibroblast growth factor (rb-bFGF) for the treatment of corneal epithelial abrasion caused by mechanical damage in Chinese patients. METHODS Thirty patients were randomly assigned to the HA or rb-bFGF treatment group. The HA group was treated with 0.3% HA and 0.5% levofloxacin...

It is a common practice to use topical anaesthetic drops to provide temporary relief and aid in the examination of the eyes when strong blepharospasm precludes thorough examination. Ophthalmology departments usually have several types of these—for example, amethocaine, oxybuprocaine (benoxinate), and proxymetacaine. The duration and degree of discomfort caused by amethocaine is significantly hi...

OBJECTIVES A prospective study to evaluate the changes in A-Scan axial parameters of phakic normal eyes before and after instillation of 1% topical Tropicamide and 2% Homatropine eye drops. METHODS Anterior chamber depth, lens thickness, vitreous chamber length, and ocular axial length were measured in 76 eyes before and after cycloplegia induced by 1% topical Tropicamide, and in 28 eyes with...

OBJECTIVE This study evaluated the efficacy and safety of a new device (Eyedrop(®)) designed for eye drop instillation in patients with and without glaucoma. METHODS This prospective study included consecutive patients with glaucoma and healthy participants. After a complete eye examination and determination of baseline intraocular pressure (IOP), topical hypotensive medication was introduced...