To gain insight into why antibody responses to malarial antigens tend to be short lived, we studied antigen-specific memory B cells from donors in an area where malaria is endemic. We compared antibody and memory B cell responses to tetanus toxoid with those to 3 Plasmodium falciparum candidate vaccine antigens: the C-terminal portion of merozoite surface protein 1 (MSP1(19)), apical membrane a...

Using the ELISA technique to estimate serum antibodies against tetanus toxin, seven neonates with clinical tetanus were found to have antibody levels 4-13 times higher than the presumed minimum protective level of 0.01 IU/ml. All but one of their mothers had been vaccinated with tetanus toxoid in pregnancy. In two other neonates, whose mothers had received multiple booster doses of toxoid durin...

Peripheral blood mononuclear cells from 46 systemic lupus erythematosus (SLE) patients showed reduced ability to proliferate in vitro in response to the soluble antigen, tetanus toxoid, as compared with 96 normal controls. Special studies of 27 untreated SLE patients also revealed significantly decreased blastogenic responses to tetanus toxoid. In both the total and untreated SLE populations, d...

1. The proportions of lymphocyte subpopulations (by rosette tests) and the serum antibody levels (using haemagglutination techniques) were estimated in malnourished and well fed Nigerian children before and up to 21 d after immunization with tetanus toxoid or measles virus vaccine. 2. Significantly diminished (P less than 0.01) mean percentage T lymphocyte levels and considerably higher mean pe...

Imunisasi Tetanus Toxoid (TT) adalah toksin kuman tetanus yang telah dimurnikan di berikan pada bayi, anak dan ibu sebagai usaha memberikan perlindungan terhadap penyakit ini juga diberikan hamil wanita akan menikah (calon pengantin). Tujuan dari penelitian untuk mengetahui faktor-faktor berhubungan dengan dalam melakukan imunisasi toxoid puskesmas pasar kota prabumulih tahun 2021. Penelitian m...

Objective(s): Drug delivery via mucosal routes has been confirmed to be effective in inducing strong immune responses. Liposomes could enhance immune responses and mucoadhesive potentials, make them useful mucosal drug delivery systems. Coating of liposomes by mucoadhesive polymers succeeded in enhancing immune responses. Our studies aim at preparation and characterization of trimethylchitosan-...