About 5-7/100,000 men are diagnosed with testis cancer annually. A large proportion of these are pathologically classified as non-seminomatous germ cell tumor (NSGCT). The majority of NSGCT patients present with clinical stage (CS) I disease, which is characterized by a germ cell tumor confined to the testis, a negative metastatic work-up which includes a chest X-ray (CXR), computed tomography ...

Herein we report a case of primary leiomyosarcoma of testis, which was believed to originate from normal testicular structures.  It contained smooth muscle cells, blood vessels and contractile cells of the seminiferous tubules.  No evidence of tumor spread was found.Treatment consisted of orchiectomy with high ligation of the spermatic cord.  The patient received no adjuvant therapy and there w...

conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...

Bone metastasis is a rare entity in germ cell tumor of testis and is a poor prognostic site. It is usually associated with synchronous metastasis at other sites. Till now very few cases of isolated bone metastasis of germ cell tumor of testis have been reported but none have reported scapular metastasis. We are reporting a case of nonseminomatous germ cell tumor of right testis that was operate...

We describe the case of a 13-year-old boy with testicular epidermoid cyst who presented with a painless testicular mass. Epidermoid cyst of the testis is a benign, non-teratomatous tumor. It is often possible to make the diagnosis preoperatively, combining typical sonographic features with normal biochemical tumor markers. Preoperative diagnosis will allow for testis-sparing surgery and prevent...

Serological screening approaches have allowed for the identification of a large number of potentially relevant tumor antigens in cancer patients. Within this group, cancer testis antigens represent promising targets for cancer immunotherapy, since they are widely expressed in a variety of human cancer entities. In pancreatic cancer, however, there are only few data available about the expressio...

A 30-day-old neonate was brought to our hospital due to testicular neoplasm in the right scrotum. Scrotal ultrasonography revealed a mixed cystic and solid mass in the testis. Analysis of testicular tumor markers was negative. Scrotal exploration was performed. A red nodular tumor was removed from the testis by surgery. Histological examination of the specimen showed it to be hemangiolymphangio...

A case of primary chondrosarcoma of the testis is reported. A 40-year-old man presented a painless swelling of the right testis that he has been observing for 3 years. Gross examination of the resected specimen showed an encapsulated, gray to tan colored, roughly rounded tumor. Histologically, the tumor revealed a well-differentiated chondrosarcoma.

OBJECTIVE Traditionally there is a concern about the possibility of developing testicular tumors as a consequence of undescended testis. This study was conducted to investigate the correlation between testicular tumors and undescended testis. METHODS Medical records of all patients with testicular germ cell cancer were seen and examined at the Princess Basma Teaching Hospital, Jordan Universi...