The pineal hormone melatonin regulates testicular function through the hypothalamic-adenohypophyseal axis. In addition, direct actions of melatonin in somatic cells of the testis have been described. Melatonin acts as a local modulator of the endocrine activity in Leydig cells. In Sertoli cells, melatonin influences cellular growth, proliferation, energy metabolism and the oxidation state, and ...

Seasonal changes in testicular and accessory gland weights, histological testicular structures, fructose and citric acid concentrations in two accessory glands and plasma testosterone levels were determined in adult male hedgehogs living in middle western France. Testicular activity started in winter (from December to February) during the last part of the hibernation period. During this resumpt...

Klinefelter syndrome (KS) is the most common genetic form of male hypogonadism, but the phenotype becomes evident only after puberty. During childhood, and even during early puberty, pituitary-gonadal function in 47,XXY subjects is relatively normal, but from midpuberty onwards, FSH and LH levels increase to hypergonadotropic levels, inhibin B decreases to undetectable levels, and testosterone ...

Testicular venous effluent was obtained by selective catheterization from 2 subjects with chromatin-positive Klinefelter's syndrome. In both of these subjects the testosterone concentration was reduced, whereas the estradiol concentration was normal or slightly increased in 1 and reduced to a much lesser extent than the testosterone level in the other. The testosterone/estradiol ratios in both ...

objective: cryopreservation of immature testicular tissue should be considered as an important factor for fertility preservation in young boys with cancer. the objective of this study is to investigate whether immature testicular tissue of mice can be successfully cryopreserved using a simple vitrification procedure to maintain testicular cell viability, proliferation, and differentiation capac...

Describe the scrotal surgical approach for abdominoscrotal hydrocele (ASH) with preservation of testicular function with midterm follow-up. Two patients diagnosed with ASH and contralateral testicular abnormalities. Both had scrotal correction for ASH, one had contralateral testicular neonatal torsion and the other contralateral communicating hydrocele. Four-year follow-up no complications or r...

Neonatal testicular torsion, also known as perinatal testicular torsion is a subject of debate among surgeons. Neonatal testicular torsion either intrauterine or postnatal results into extravaginal torsion which is a different entity than intravaginal type but has the same devastating consequences if not diagnosed and managed well in time. Testicular torsion results into acute ischemia with its...

Larger testes are considered the quintessential adaptation to sperm competition. However, the strong focus on testis size in evolutionary research risks ignoring other potentially adaptive features of testicular function, many of which will also be shaped by post-mating sexual selection. Here we advocate a more integrated research programme that simultaneously takes into account the development...

The objective of this study was to determine the appropriate non-linear function describing growth of some testicular traits (testicular length, testicular diameter, scrotal circumference and scrotal length) in Norduz male lambs. Testicular characteristics at 90, 110, 130, 150, 170, and 190 days of age for all the lambs were measured. Four growth (Monomolecular, Logistic, Gompertz, and Richard’...

Emerging evidence suggests that dietary fats may influence testicular function. However, most of the published literature on this field has used semen quality parameters as the only proxy for testicular function. We examined the association of fat intake with circulating reproductive hormone levels and testicular volume among healthy young Spanish men. This is a cross-sectional study among 209 ...