and Chamberlin. Indeed, we provided evidence that propofol anesthesia desynchronized the circadian rhythms of rest-activity and body temperature in rodents in the experimental condition of either alternation of light/dark or constant darkness. By citing the study of Sessler et al. of 1991, they create the impression that anesthetic exposure does not affect the circadian rhythms in humans. It mu...

PURPOSE Ice Water Test (IWT) is not frequently used today. IWT triggers a non-inhibited involuntary detrusor contraction (NIDC) when the bladder is being filled with cold saline solution. NIDC is unmasked via a segmental reflex loop different from the physiological micturition reflex. Our purpose was to search for usefulness of IWT to expose detrusor overactivity (DO). METHODS One hundred and...

Experience with the DOCA test (measurement of urinary excretion of aldosterone before and after 3 days of administration of 10 mg deoxycorticosterone acetate [DOCA] intramuscularly every 12 hours while on high sodium intake) is presented in 129 hypertensive patients to define its usefulness in discriminating between autonomous and nonautonomous production of aldosterone. All patients who did no...