The exchange of the monocarboxylate ligand of the zirconium methacrylate oxocluster Zr(6)O(4)(OH)(4)(OMc)(12) (OMc = CH(2)=CH(CH(3))COO) with dicarboxylic acids (trans,trans muconic acid and terephthalic acid) leads to porous zirconium dicarboxylates exhibiting the UiO-66 architecture; the mild reaction conditions allow the control of their particle size.

While the current supramolecular syntheses of [2]rotaxanes are generally efficient, the final product always retains the functional groups required for non-covalent preorganization. A short and high-yielding covalent-template-assisted approach is reported for the synthesis of a [2]rotaxane. A terephthalic acid template core preorganizes the covalently connected ring precursor fragments to induc...

In the title compound, 2C(8)H(7)N(3)·C(8)H(6)O(4)·2H(2)O, the pyridine and pyrazole rings are approximately coplanar, the dihedral angle between them being 4.69 (9)°. The asymmetric unit consists of half of the terephthalic acid (an inversion centre generates the other half of the mol-ecule), one 4-(1H-pyrazol-3-yl)pyridine (4pp) mol-ecule and one water mol-ecule. In the crystal, two 4pp and on...

Terephthalic acid (TPA) is an important industrial chemical currently produced by energy intensive and potentially hazardous p-xylene (pX) oxidation process. Here we report the development of metabolically engineered Escherichia coli system for biological transformation of pX into TPA. The engineered E. coli strain harbours a synthetic TPA pathway optimized through manipulation of expression le...