Oxygen abundances have been derived from the near-IR, high-excitation λ7774 O I triplet in high-resolution, high signal-to-noise spectra of 45 Hyades dwarfs using standard one dimensional, plane-parallel LTE models. Effective temperatures of the stellar sample range from 4319 − 6301 K, and the derived relative O abundances as a function of Teff evince a trichotomous morphology. At Teff > 6100 K...

Abolishing the inhibitory signal of intracellular cAMP is a prerequisite for effector T (Teff) cell function. The regulation of cAMP within leukocytes critically depends on its degradation by cyclic nucleotide phosphodiesterases (PDEs). We have previously shown that PDE8A, a PDE isoform with 40-100-fold greater affinity for cAMP than PDE4, is selectively expressed in Teff vs. regulatory T (Treg...

In previous work, Gardiner et al. (1999) found evidence for a discrepancy between the Teff obtained from Balmer lines with that from photometry and fundamental values for A-type stars. An investigation into this anomaly is presented using Balmer line profiles of stars in binary system with fundamental values of both Teff and log g. A revision of the fundamental parameters for binary systems giv...

Multiple sclerosis (MS) is a chronic autoimmune disease caused by an insufficient suppression of autoreactive T lymphocytes. One reason for the lack of immunological control is the reduced responsiveness of T effector cells (Teff) for the suppressive properties of regulatory T cells (Treg), a process termed Treg resistance. Here we investigated whether the disease-modifying therapy of relapsing...

We consider the effects of convection on the Balmer line profiles (Hα and Hβ) of A, F, and G stars. The standard mixing-length theory (MLT) atlas9 models of Kurucz (1993), with and without overshooting, are compared toatlas9models based on the turbulent convection theory proposed by Canuto & Mazzitelli (1991, 1992) and implemented by Kupka (1996), and the improved version of this model proposed...

We present atmospheric parameters for about 300 stars of different chemical composition, whose spectra will be used to study the galactic enrichment of Fe and light elements. These parameters were derived using an homogenous iterative procedure, which considers new calibrations of colour-Teff relations for F, G and K-type stars based on Infrared Flux Method (IRFM) and interferometric diameters ...

Introduction Autoimmune diseases are characterized by an imbalance between regulatory T cells (Treg) and effector T cells (Teff) both in terms of number and function. Our group previously showed that Teff from the site of inflammation (i.e. synovial fluid, SF) of patients affected by Juvenile Idiopathic Arthritis (JIA) are resistant to autologous Treg-mediated suppression irrespective of the so...

Using population synthesis tools we create a synthetic Kepler Input Catalogue (KIC) and subject it to the Kepler Stellar Classification Program (SCP) method for determining stellar parameters such as the effective temperature Teff and surface gravity g. We achieve a satisfactory match between the synthetic KIC and the real KIC in the log g versus log Teff diagram, while there is a significant d...

Introduction Resistance of effector T cells (Teff) to suppression contributes to disturbed immune regulation in autoimmune disease. Targeting this unresponsiveness to suppression might therefore have beneficial effects in autoimmune inflammation. In juvenile idiopathic arthritis (JIA) we have recently shown that Teff from inflamed joints are refractory to suppression, which was associated with ...

Lithium abundances in a sample of halo dwarfs have been redetermined by using the new Teff derived by Fuhrmann et al (1994) from modelling of the Balmer lines. These Teff are reddening independent, homogeneous and of higher quality than those based on broad band photometry. Abundances have been derived by generating new atmospheric models by using the ATLAS-9 code by Kurucz (1993) with enhanced...