Для эффективной борьбы с тейлериозом крупного рогатого скота необходимы мероприятия по предотвращению распространения инфекции на благополучные регионы. В этой ситуации важным моментом является проведение систематических и достаточно масштабных серологических исследований восприимчивого поголовья, для чего необходимо наличие у ветеринарных специалистов высокочувствительных специфичных диагности...

The concept of template-assembled synthetic proteins (TASP) describes a central scaffold that predefines the three dimensional structure for diverse molecules linked to this platform. Cyclic β-tripeptides are interesting candidates for use as templates due to their conformationally defined structure, stability to enzymatic degradation, and ability to form intermolecular stacked tubular structur...

INTRODUCTION The use antiretroviral reduces the sexual transmission of HIV, expanding interventions for serodiscordant couples. OBJECTIVE This article aims to review the use of antiretroviral and other prevention interventions among serodiscordant couples and to analyze its use in Brazil. METHODS A retrospective review was performed through the MEDLINE database and bases included in the Bib...

The ultimate goal in protein de novo design is the Construction of artificial proteins exhibiting tailor-made structural and functional properties. To create nativelike macromolecules in copying nature's way has proven to be difficult because the mechanism of folding in its complexity has yet to be unravelled. In the present review we describe a conceptually different approach in protein design...

Men's poorer engagement with healthcare generally and HIV care specifically, compared to women, is well-described. Within the HIV public health domain, interest is growing in universal test and treat (UTT) strategies. UTT strategies refer to the expansion of antiretroviral therapy (ART) in order to reduce onward transmission and incidence of HIV in a population, through a "treatment as preventi...

background: a major issue in many gene expressionstudies utilizing small amount of biological materials is thelimited quantity of rnapurified from clinical samples, which isoften used for rt-pcr or standard northern blot analysis.objectives: the smart cdna synthesis method and subsequentsmart-cdna-pcr technique was used to analyse 3genes in macroschizonts of theileria annulata in small lymphnod...

BACKGROUND The Universal HIV Test and Treat (UTT) strategy represents a challenge for science, but is also a challenge for individuals and societies. Are repeated offers of provider-initiated HIV testing and immediate antiretroviral therapy (ART) socially-acceptable and can these become normalized over time? Can UTT be implemented without potentially adding to individual and community stigma, o...

In the spring of 1996, the National Center for Developmental Education (NCDE) was contracted by the Texas Higher Education Coordinating Board (THECB) to conduct an extensive evaluative study of the Texas Academic Skills Program (TASP). The study was completed in October of 1996 and findings were then shared with the Coordinating Board, the Texas Legislature, and Texas public colleges and univer...

Treatment as prevention (TasP) not only stands for prevention of HIV transmission by treating HIV-positives, but also for prevention of morbidity and mortality in those positives. Mathematical models have shown that it should be possible to “eradicate” HIV at the population level, or at least come close to it, if this approach were rigorously applied. But these optimistic models are based on as...

When adhered to consistently, ART can reduce the HIV viral load in an individual’s blood, semen, vaginal fluid and rectal fluid to such a low level that blood tests can’t detect it.1 This is described as an 'undetectable' viral load or viral suppression. In these circumstances, as long as someone’s viral load remains undetectable, their health will not be affected by HIV and they cannot transmi...