Two effective cytochrome P450 (CYP) inhibitors were isolated from tarragon, Artemisia dracunculus. Their structures were spectroscopically identified as 2E,4E-undeca-2,4-diene-8,10-diynoic acid isobutylamide (1) and 2E,4E-undeca-2,4-diene-8,10-diynoic acid piperidide (2). Both compounds had dose-dependent inhibitory effects on CYP3A4 activity with IC50 values of 10.0 ± 1.3 µM for compound 1 and...

this study was performed to assess the effects of nitrogen fertilizer and vermicompost on qualitative and quantitative yield of chamomile ( matricaria chamomilla l.). it was conducted at the research fields of ran company located in firouzkouh, iran, in 2013. treatments were consisted of 1) control, 2) 100% nitrogen from urea, 3) 100% nitrogen from ammonium nitrate, 4) 75% nitrogen from urea an...

objective: this study was designed to investigate the effect of hydroalcoholic extract and essential oil of heracleum persicum (apiaceae) on lipid profile of male hyperlipidemic rabbits. materials and methods: thirty rabbits were randomly divided into six groups of five each. one group received normal diet and the other groups fed with a high cholesterol (2% w/w) diet for 7 weeks. vehicle, hydr...

phytochemicals are good sources of natural antioxidants and have beneficial effects on human health. many of phenolic phytochemicals have shown antimicrobial and antifungal activity. anise hyssop ( agastache foeniculum [pursh] kuntze ) is a perennial aromatic plant of the lamiaceae family with antimicrobial and antifungal properties and useful for gastrointestinal problems. in this investigatio...

Environmental and water pollution through heavy metals is a growing concern. The recycling of untreated wastewater, which is often contaminated with heavy metals, for agricultural applications is becoming more popular. However, information on the amount of absorption and accumulation of cadmium (Cd) at variable concentrations by different crops is limited. This study aims to analyze the impact ...

this study was designed to investigate the effects of different levels of tarragon powder on performance, carcass characteristics of broiler chickens. two hundred ross 308 male broiler chickens were randomly allocated into four treatments and five replicates per treatment. at each replicate ten birds were used. experimental diets were set on the basis of corn-soy-wheat and ross 308 broiler chic...

BACKGROUND Essential oils are used in perfumery and in products for aromatherapy or balneotherapy. Previous studies have shown some to be important contact sensitizers. A practical diagnostic approach, based on the results of a large, central European network and other evidence, is needed. METHODS Data of the Information Network of Departments of Dermatology (IVDK; www.ivdk.org) on all patien...