نتایج جستجو برای: targeting effect
تعداد نتایج: 1773261 فیلتر نتایج به سال:
Malignant tumor (cancer) remains as one of the deadliest diseases throughout the world, despite its overall mortality drops. Nanomaterials (NMs) have been widely studied as diagnostic and/or therapeutic agents for tumors. A feature of NMs, compared to small molecules, is that NMs can be concentrated passively in tumors through enhanced permeability and retention (EPR) effect. In the meantime, N...
Low and stable inflation rates are essential to promote economic growth and welfare of the people. Therefore, many countries pursue their policies within the framework of inflation targeting to achieve low and stable inflation rates. Monetary policy implementation based on inflation targeting is a framework that has been adopted by many countries since 1990. To implement such framework, a serie...
there is less published research about how teachers in efl contexts respond to students who are relatively less mature and less competent l2 writers. while writing researchers have examined various issues concerning peer and teacher response in writing-oriented classes, little research has centered on the effect of collaborative tasks particularly dictogloss on writing skills. output collaborat...
Effective delivery of nanoparticles to the target site is necessary for successful biomedical applications. Inefficient targeting is a major concern for nanomedicines in cancer therapy. Conjugation of multiple targeting ligands to the nanoparticle surface might further enhance the targeting efficiency by a co-operative effect of individual ligands. In this study, a dual ligand targeting nanogra...
Active targeting of nanoparticles to tumours can be achieved by conjugation with specific antibodies. Specific active targeting of the HER2 receptor is demonstrated in vitro and in vivo with a subcutaneous MCF-7 breast cancer mouse model with trastuzumab-functionalized gold nanoparticles. The number of attached antibodies per nanoparticle was precisely controlled in a way that each nanoparticle...
the implementation of economic projects by targeting the subsidies can have a great effect on the costcompetitiveness of the industries and their products. the global steel industry has been considered as a basickey industry in the industrialized countries. it is also among the industries that may be seriously affected by theenforcement of subsidies. this industry, requiring energy and high-tec...
Three alpha particles are emitted from the P-11B fusion reaction. Alpha particles play an important role in the death of cancer cells. When boron is accumulated in the tumor, protons irradiated out of body can react with the boron in the tumor. Also a fast gamma ray of 719 KeV beam is released from the P-11B fusion reaction which plays a useful role for us. This therapeutic approach includes fe...
abstract: advertisements are the most accessible type of authentic materials, and this is one reason why they are used more and more in english teaching classes. for this cause, studies in the field of advertisements are very widespread nowadays. for pun is one aspect which makes advertisements more interesting, it is used more than before in advertisements. use of puns makes an advertisement m...
Dipeptidyl peptidase IV (DPPIV) is mainly vectorially targeted to the apical surface in MDCK cells. BFA was found to abolish the apical targeting of DPPIV. This BFA effect could be achieved under conditions where the ER to Golgi transport and the total surface expression of DPPIV were essentially unaffected. BFA executed its effect during the transport from the trans-Golgi network (TGN) to the ...
Purpose Transforming growth factor β (TGFβ) is upregulated in many types of tumors and plays important roles tumor microenvironment construction, immune escape, invasion, metastasis. The therapeutic effect antibodies nuclide-conjugated drugs targeting TGFβ has not been ideal. Targeting with small-molecule or peptide carriers labeled diagnostic/therapeutic nuclides a new development direction. T...
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