BACKGROUND Opuntia elatio Mill is a xerophytic plant with potentially active nutrients. It is traditionally appreciated for its pharmacological properties; however, the scientific information on this plant is insufficient. OBJECTIVE The present study evaluates the antinociceptive and anti-inflammatory action of prickly pear. MATERIALS AND METHODS Writhing and tail-immersion tests were carri...

In folk medicine, Polyalthia suberosa is used as abortifacient, laxative, febrifuge analgesic, filler of tooth cavities, and anti-HIV drug and for rheumatism and various skin infections. The present study was directed to evaluate the analgesic and anti-inflammatory activities of diethyl ether and n-hexane extracts of Polyalthia suberosa leaves (PSDE and PSNH). A variety of tests including forma...

Transcutaneous electrical nerve stimulation (TENS) is an analgesia inducing method with increasing applications in clinical procedures. In this study we tried to evaluate the role of the adrenergic system and its different adrenoceptor subtypes in TENS-induced analgesia. Two types of low and high frequency electrical stimuli were used in rats through needle electrodes, inserted at the base ...

BACKGROUND Persicaria hydropiper (Linn.) Delarbre is a common plant of Polygonaceae family commonly called Bishkatali in Bangladesh. Leaves of the plant are traditionally used in the treatment of rheumatic pain, gout, and skin diseases such as ringworms, scabies, boils, abscesses, carbuncles, bites of snakes, dogs or insects. This study evaluated the antinociceptive effect of the methanol extra...

objective: this study was designed to investigate the antinociceptive effect of curcumin in diabetic rats by using the formalin and hot tail immersion tests. methods: wistar rats were divided into the following six groups:  control; curcumin-treated control (50 mg/kg); diabetic; sodium salicylate (ss)-treated diabetic; and two curcumin-treated diabetic groups (10 and 50 mg/kg). curcumin was ad...

Moringa stenopetala (Baker f.) Cufod., is an endemic species growing in the south of Ethiopia. M. often consumed as food and used traditional medicine it has also been traditionally for relieving pain This study aimed to investigate antinociceptive effect mechanisms action leaves methanol extract mice. The per-oral doses 50, 100, 200 mg/kg were tested by using hot-plate, tail-immersion, writhin...

Introduction. Microcos paniculata is traditionally used for treating diarrhea, wounds, cold, fever, hepatitis, dyspepsia, and heat stroke. Objective. To investigate the qualitative phytochemical constituents of hydromethanol (HMPB) and petroleum benzene extract of Microcos paniculata barks (PBMPB) and to evaluate their antinociceptive and antidiarrheal activities. Methods. Phytochemical constit...

BACKGROUND Vanda tessellata (Orchidaceae) has been used in different sorts of ailments such as inflammations, rheumatism, dysentery, bronchitis, dyspepsia and fever in folk medicine. In this study we evaluated the antinociceptive and cytotoxic effect of methanol and aqueous extracts of V. tessellata leaf. METHODS Oral administration of V. tessellata aqueous (VTA) and methanol (VTM) leaf extra...

BACKGROUND Various parts of Pandanus foetidus Roxb. are used as traditional medicines. However, scientific reports concerning the effect of this plant on central nervous system (CNS) depression and analgesia are unavailable. This study investigated the CNS depressant and antinociceptive effects of Pandanus foetidus leaf extracts in a rodent model. METHODS The sedative and anxiolytic activitie...