Recent studies have indicated that acute inhibition of nitric oxide biosynthesis in the rat promotes arterial hypertension and renal vasoconstriction. We evaluated the renal and systemic effects of 4-6 weeks of nitric oxide blockade in Munich-Wistar rats receiving the nitric oxide inhibitor nitro-L-arginine orally. Age-matched untreated rats were used as controls. In an additional seven rats, n...

To evaluate the effect of chronic hyperinsulinemia on blood pressure in salt-dependent hypertension, we infused insulin (1.0 IU/d, n = 15) or saline (n = 13) for 4 weeks into deoxycorticosterone acetate-salt hypertensive rats. The insulin infusion increased plasma insulin levels to 24 +/- 2 microU/mL, which was higher than in the saline-infused rats (9 +/- 1 microU/mL) but was still within the ...

Arat’s tail is a slender appendage on which the weight of so much research in hypertension hangs, yet blood pressure measurements recorded from it are usually taken for granted, often abused, but seldom discussed,” observed Buang in an earlier commentary.1 The same methodology has now been adapted to mice. Restraining the animals is a serious problem. A 7-day training period is recommended to a...

background untrained fingertip palpation has been shown to be unable to adjust endotracheal tube (et) cuff pressure in most intubated patients. objective we determined the impact of a training course of ett cuff adjustment by palpation in attaining a safe cuff inflation pressure. patients and methods twenty-five nurses were asked to adjust the ett cuff pressure to 25 cmh2o by palpation on three...

Background: Successful repair of a torn rotator cuff may prevent progression to rotator cuff arthropathy. However,previous studies have shown a substantial rate of failure after rotator cuff repair and characteristics of surgicallyrepaired rotator cuffs that go on to shoulder arthroplasty have not been fully elucidated. The purpose of this study wasto determine the patient cha...

CONTEXT Animal models for essential hypertension have been used for understanding the human pathological conditions observed in pregnant hypertensive women. OBJECTIVE To study the possible effects of pregnancy on hypertension and of hypertension on pregnancy in spontaneously hypertensive rats (SHR), and in their normotensive Wistar-Kyoto (WKY) counterparts. TYPE OF STUDY Comparative study u...

We previously detected by linkage analysis in segregating populations derived from crosses between the Sabra hypertension-prone rat (SBH/y) and the hypertension-resistant strain (SBN/y) two QTLs for salt susceptibility on chromosome 1, with sex specificity: in males SS1a and SS1b, and in females SS1b only. To provide support for a functional role of these QTLs in relation to hypertension, we co...

abstract  background: rotator cuff tear is one of the most common causes of shoulder  complaints in the elderly. based on the severity and patient's condition, a variety of  methods applies to manage the tear and surgery is an important method, which could  be done by open or arthroscopic technique. the current study aimed to investigate  and report short-term results of arthroscopic repair of ...