Reversible lysine acetylation is one of the most widely distributed post-translational modifications; it is involved in a variety of biological processes and can be found in all three domains of life. Acetyltransferases and deacetylases work coordinately to control levels of protein acetylation. In this work, we applied the genetic code expansion strategy to site-specifically incorporate Nε-thi...

We present a simple technique to switch off the tack adhesion in selected areas of a colloidal nanocomposite adhesive. It is made from a blend of soft colloidal polymer particles and hard copolymer nanoparticles. In regions that are exposed to IR radiation, the nanoparticles sinter together to form a percolating skeleton, which hardens and stiffens the adhesive. The tack adhesion is lost locall...

There have been a variety of absorbable and permanent tacks, tack deployment systems, and fasteners developed for the fixation of mesh during laparoscopic ventral hernia repair. The manufacturer recommendation for all systems is for perpendicular deployment of these tacks into the tissue. Achieving this optimal angle with previously developed deployment systems is often challenging and can lead...

A tack coat is a thin cut-back cement or asphalt emulsion coating applied on an existing non-absorbent pavement. good bonding between the and concrete necessary to provide sufficient structural strength. Poor adhesion will result in shear failure. The test one of basic tests determine bond This study aims quantify best resistance obtained using three types asphalts (RC70, RC800 modified with po...