Endocrine tumours of the pancreas, even in case of liver involvement, are generally characterized by a slower evolution and a better prognosis, if compared with ductal carcinoma. This fact gives reason to a radical surgical approach, whenever possible, and to the research of any effective adjuvant treatment. For this purpose, hepatic transarterial chemoembolization (TACE) has been proposed in r...

BACKGROUND The prognosis of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE) is variable, despite a myriad of prognostic markers. We compared and integrated the established prognostic models, HAP and ART scores, for their accuracy of overall survival (OS) prediction. RESULTS In both training and validation sets, HAP and ART scores emerged as indep...

background : transarterial chemoembolization is the preferred treatment for unresectable, intermediate-stage hepatocellular carcinoma. survival after transarterial chemoembolization can be highly variable. the purpose of this study is to identify the factors that predict overall survival of patients with unresectable hepatocellular carcinoma who undergo transarterial chemoembolization as the in...

The aim of this study was to present our single center experience with short (< 3 months) and intermediate-term (> 3 months) follow-up results of patients who underwent transarterial radioembolization with yttrium-90 microsphere (Y-90) or transarterial chemoembolization (TACE) for hepatic metastasis of neuroendocrine tumors (hmNETs). The results of 14 patients treated with either Y-90 or TACE w...

We report the case of a 78-year-old woman with hepatocellular carcinoma who underwent drug-eluting bead transarterial chemoembolization (DEB-TACE). On the first routine follow-up CT six-weeks post procedure, the patient was found to have residual enhancing tumor and active intra-tumoral hemorrhage (Fig 1A). Follow-up laboratory values demonstrated a decrease in hemoglobin. Subsequent catheter a...

Transarterial chemoembolization (TACE) is the standard treatment for intermediate stage, although the combination of TACE with sorafenib may theoretically benefit HCC patients in intermediate stage. Owing to the significant antiangiogenic effect of sorafenib and the limitation of TACE, it is rational to combine them. Though the strategy of combining TACE and sorafenib has been increasingly used...

STUDY DESIGN Previous works suggested that neutralizing intratumoral lactic acidosis combined with glucose deprivation may deliver an effective approach to control tumor. We did a pilot clinical investigation, including a nonrandomized (57 patients with large HCC) and a randomized controlled (20 patients with large HCC) studies. METHODS The patients were treated with transarterial chemoemboli...

BACKGROUND The prognosis for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor. OBJECTIVES This study aimed to evaluate the safety and effectiveness of transarterial ethanol ablation (TEA) for the treatment of HCC with PVTT. METHODS Patients were treated with TEA for PVTT under cone-beam computed tomography and traditional transarterial chemoembolizat...

Current treatment of HCC is based on the updated Barcelona algorithm [3]. According to this algorithm, therapeutic options for HCC are divided into curative treatments (resection, liver transplantation and radiofrequency/percutaneous ethanol injection) for HCC in very early stage or early stage (A), transarterial chemoembolization (TACE) for intermediate stage (B) HCC, sorafenib for advanced st...

A 71-year-old female was diagnosed with hepatocellular carcinoma (HCC). The tumor measured 65 mm in diameter and was located in the caudate lobe. Transarterial chemoembolization (TACE) was performed repeatedly; however, a follow-up dynamic computed tomography (CT) scan showed that the tumor remained viable. Thus, TACE was performed using drug-eluting beads that had been preloaded with epirubici...