A patient with inappropriate thyrotrophin (TSH) secretion is described. She initially presented with classical hyperthyroidism during pregnancy, responded to propylthiouracil and, subsequently, had a normal delivery. Hyperthyroidism persisted and 7.5 months later a subtotal thyroidectomy was performed. After a further 16 months, mild symptoms of hyperthyroidism recurred. She again responded to ...

AIMS Altered thyroid hormone metabolism characterized by a low triiodothyronine (T3), so-called low-T3 syndrome, is a common finding in patients with severe systemic diseases. Additionally, subclinical thyroid dysfunction, defined as abnormal thyroid stimulating hormone (TSH) and normal thyroxine (T4), causes left ventricular dysfunction. Our objective was to identify the prevalence and prognos...

Because little has been published on early effects of treatment with amiodarone on thyroid function, we studied serum total and free thyroid hormone, reverse T3, and TSH levels in patients with cardiac arrhythmias during the first 10 days of treatment with a loading dose of amiodarone by iv infusion. Twenty-four patients were enrolled in the study. A standardized loading regimen for the i.v. in...

background: since the introduction of the first radioimmunoassay, several improvements have been made in the design of immunoassays such as method of antibody production, labeling, automation and detection technology. we performed an analytical evaluation of the new electrochemiluminescent immunoassay (eclia) for serum tsh, ft4 and t3 in the elecsys 2010 immunoassay system and compared the resu...

The elevated fluoride from drinking water impacts on T3, T4 and TSH hormones. The aim was study impacts of drinking water fluoride on T3, T4 and TSH hormones inYGA (Yazd Greater Area). In this case- control study 198 cases and 213 controls were selected. Fluoride was determined by the SPADNS Colorimetric Method. T3, T4 and TSH hormones tested in the Yazd central laboratory by RIA (Radio Immuno ...

Background. Nitric oxide (NO) plays an important role in various biological processes. It has been suggested that NO may modulate the functions of the endocrine system. The aim of this study was to examine the role of nitric oxide in total triiodothyronine (T3), free thyroxine (fT4) and TSH secretion in adult female Wistar rats. Material and Methods. The animals were treated with L−NAME (10 mg/...

The effects of interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF alpha) on basal and TRH-induced TSH release, and the effects of IL-1 beta on the uptake of [125I]T3 and [125I]T4 and on nuclear binding of [125I]T3 were examined. Furthermore, the release of other anterior pituitary hormones in the presence of IL-1 beta was measured. Anterior pituitary cells from male Wistar rats...

Serum thyroid hormone levels have been assayed to evaluate the thyroid hormonal function in Vitiligo patients of Bangladesh. The levels of TSH, T3 and T4 in the serum of Vitiligo patients have been analyzed in both the male and female subjects. Results of hormonal assay indicated that some hormonal changes occurred in the Vitiligo patients as compared with the healthy control. In female Vitilig...