INTRODUCTION AND OBJECTIVES Most studies have shown that prognosis of heart failure with preserved systolic function is as poor as that of heart failure with depressed systolic function, although these results may be biased by the fact that these types of heart failure have different characteristics (age, comorbidity, treatment), which can influence prognosis. Our aim was to determine whether s...

But what do we do when one number is at goal and the other is not? It is clear that in individuals younger than 50 years, diastolic BP (DBP) is the better predictor of future complications of hypertension, whereas in those 50 years and older, systolic BP (SBP) is a better predictor of future complication risk. Most individuals with hypertension are 50 years or older, and for these patients, SBP...

OBJECTIVE To delineate more precisely an operational threshold for making clinical decisions based on ambulatory blood pressure (ABP) measurement by studying the ABP in subjects who were diagnosed as either normotensive or hypertensive by conventional blood pressure (CBP) measurement. SUBJECTS Twenty-four research groups recruited 7069 subjects. Of these, 4577 were normotensive (CBP < or = 14...

heart failure is common in patients with chronic renal disease, either as a complication of renal failure or from shared risk factors, or is the major cause of death in patients on dialysis. at present, end stage renal disease (esrd) patients who have systolic heart failure are considered high-risk for surgery; and nephrologists and cardiologists are reluctant to refer these patients for kidney...

OBJECTIVE To test the hypothesis that, when measured in the long axis, left ventricular systolic function is abnormal in patients with diastolic heart failure. DESIGN A case-control study. SETTING University teaching hospital (tertiary referral centre). PATIENTS 68 patients with heart failure, 29 with a left ventricular ejection fraction (LVEF) of > 0.45 and diastolic dysfunction (diastol...

* Programa de Pós-graduação em Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG) and ArcelorMittal Abeb and Hospital Life Center, Belo Horizonte, MG, Brazil. ** Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. *** Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmáci...

BACKGROUND Regarding the relationship between blood pressure (BP) and shift work (SW), previous studies have reported contradictory results. In the present study, we used Bayesian multilevel modeling to evaluate the association of SW and BP after controlling some confounding factors. METHODS Data of this multicenter historical study were extracted from annual observations of the male workers ...

High blood pressure (BP), a major established predictor of cardiovascular disease, is the leading risk factor for mortality worldwide.1,2 Both systolic BP (SBP) and diastolic BP (DBP) have continuous, independent relations with the risk of cardiovascular disease3; however, considerable uncertainty persists about the relative importance of SBP, DBP, and their combination in predicting cardiovasc...

Diastolic heart failure occurs when signs and symptoms of heart failure are present but left ventricular systolic function is preserved (i.e., ejection fraction greater than 45 percent). The incidence of diastolic heart failure increases with age; therefore, 50 percent of older patients with heart failure may have isolated diastolic dysfunction. With early diagnosis and proper management the pr...