Lupus erythematosus panniculitis (profundus), a rare variant of chronic panniculitis, sometimes develops during the course of discoid lupus erythematosus or systemic lupus erythematosus. A 61-year-old woman had suffered from autoimmune hepatitis type I for 5 years. Prednisolone had been administered as maintenance therapy and her hepatitis had been well controlled. However, asymptomatic erythem...

Lupus nephritis is a serious potential feature of systemic lupus erythematous (SLE). Though SLE typically cycles through periods of flares and remission, patients often eventually succumb to end-stage kidney or cardiovascular damage. This review of the pathogenesis of lupus nephritis examines the role of the complement cascade; the significance of autoantibodies, the breaking of tolerance, and ...

Lupus nephritis is a serious potential feature of systemic lupus erythematous (SLE). Though SLE typically cycles through periods of flares and remission, patients often eventually succumb to end-stage kidney or cardiovascular damage. This review of the pathogenesis of lupus nephritis examines the role of the complement cascade; the significance of autoantibodies, the breaking of tolerance, and ...

Introduction The most widely used classification criteria for systemic lupus erythematous (SLE) are those derived and validated in adult patients, by the American College of Rheumatology (ACR). However, some of their limitations raise concerns, such as: inclusion of the most typical features only, possible duplication of highly correlated cutaneous manifestations, omission of many neurologic ma...

Systemic Lupus Erythematous can present with psychiatric symptoms. As these symptoms are non-specific and may occur in the absence of clear systemic signs and symptoms of lupus, they are difficult to distinguish from primary psychiatric illnesses. We present the case of a young woman who, on two separate admissions, was treated for a psychiatric illness with no effect and then treated for Neuro...

BACKGROUND Systemic lupus erythematodes (SLE) is chronic, often febrile, multisystemic disease unknown origin and relapsing course which affects connective tissue of the skin, joints, kidney and serous membranes. Gastrointestinal manifestations are rarely the first sign of systemic lupus erythematosus. CASE REPORT We presented a female patient, 35 years old, whose first symptoms of SLE were p...