background & objectives: colon cancer is currently of high incidence and mortality rate. identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. the aim of the present study is to investigate the effect of this factor on the prognosis of the patie...

BACKGROUND: Bladder cancer is one of the most common malignancies in Western society. In the United States, approximately 10,000 of these patients present with invasive disease, and more progress from superficial bladder cancer. METHODS: The authors review the literature on systemic treatment for both localized and metastatic bladder cancer, and they include their experience in defining approac...

INTRODUCTION The SCAN gynaecological cancers systemic therapy workgroup aimed to develop Singapore Cancer Network (SCAN) clinical practice guidelines for the systemic therapy of endometrial (uterine) cancer. MATERIALS AND METHODS The workgroup utilised a modified ADAPTE process to calibrate high quality international evidence-based clinical practice guidelines to our local setting. RESULTS ...

OBJECTIVE The median survival of leptomeningeal metastases is short despite therapy and is sometime associated with hydrocephalus. We investigated the prognostic significance of surgically treated hydrocephalus in leptomeningeal metastases. MATERIALS AND METHODS Between December 2005 and November 2012, 1343 patients had brain metastases from systemic solid tumors. Of these, 71 patients (5.3%)...

BACKGROUND Inflammation may play an important role in cancer progression, and a higher systemic immune-inflammation index (SII) has been reported to be a poor prognostic marker in several malignancies. However, the results of published studies are inconsistent. MATERIALS AND METHODS A systematic review of databases was conducted to search for publications regarding the association between blo...