A procedure for the radiosynthesis of aliphatic [(18)F]trifluoromethyl groups by reacting 1,1-difluorovinyl precursors with [(18)F]fluoride ions, resulting in the equivalent of direct nucleophilic addition of H[(18)F]F, has been developed. A variety of (18)F-labelled model compounds were then obtained and two potential [(18)F]radiotracers were synthesised by a two step process starting from 1,1...

3-Substituted Indoles, Indole Alkaloids, UV Spectra, MS Spectra, 1H NMR spectra Methods are described which allow the synthesis of several plant indole alkaloids and their metabolites at different scales. Compounds synthesized include gramine (1) (3-dimethylaminomethylindole) which is directly derived from indole, while its biosynthetic precursors 3-aminomethylindole (3) and 3-methylaminomethyl...

1. Measurements of the net synthesis of glucose plus glycogen from various precursors in slices of glycogen-depleted livers from rats at various stages of development indicated an increase in the gluconeogenic capacity after birth with l-lactate, oxaloacetate, a casein hydrolysate, l-serine, l-threonine, l-alanine and glycerol as substrates. 2. The highest rates of incorporation of (14)C-labell...

The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO₂-labelling experiments using wildtype and transgenic plants overexpressing the 3-hydroxy-3-methylglutaryl CoA reductase (HMGR), the first and key enzyme of the MVA pathway. The plants were labelled in the presence o...

The biosynthetic pathways involved in the formation of four everninomicin antibiotics were studied. Carbon-14 labelled substrates added to liquid cultures of Micromonospora carbonacea var. aurantiaca revealed that acetate, malonate and glucose were good precursors. Degradation of the antibiotics revealed the primary importance of acetate and malonate for the synthesis of the dichloroisoevernini...

In the present work, we report the synthesis of binary nano metal oxides such as Zinc /Copper Oxide via novel dry synthetic methods such as thermal decomposition of oxalate precursor. The synthesis route involves facile solid-phase mechanochemical activation of a physical mixture of simple copper/zinc salts and oxalic acid, followed by calcination of the as-ground oxalate precursors at 450◦C. X...

The ability to mix multiple elements in a structure is crucial for obtaining Cu-based nanostructures and microstructures with desirable physicochemical properties. Precursors containing metal cations, such as layered double hydroxides, have been used the synthesis of multielement materials. However, these precursors experience difficulty large which limits functionalities derived Herein, develo...

Nanocrystalline cobalt ferrite as a magnetic black pigment was synthesized via coordinated precursors with a significant decrease of the synthesis temperature using citric acid as a coordinating agent. The structure and properties of the cobalt ferrite powder were characterized by X-ray diffraction (XRD), colorimetric analysis (L*a*b* color parameters), diffuse reflectance spectroscopy and vibr...