A novel thermo-sensitive superabsorbent hydrogel with saltand pH-responsiveness properties was obtained by grafting of mixtures of acrylic acid (AA) and N-isopropylacrylamide (NIPAM) monomers onto kappa-carrageenan, kC, using ammonium persulfate (APS) as a free radical initiator in the presence of methylene bisacrylamide (MBA) as a crosslinker. Infrared spectroscopy was carried out to confirm t...

Aloe vera-based hydrogels have emerged as promising platforms for the delivery of therapeutic agents in wound dressings due to their biocompatibility and unique wound-healing properties. The present study provides a comprehensive overview recent advances application healing. synthesis methods, structural characteristics, properties are discussed. Mechanisms released from hydrogels, including di...

Rheumatoid arthritis, an autoimmune inflammatory disorder is characterized by progressive cartilage erosion leading to joint destruction, pain, stiffness, and swelling. Although the etiology of disease unknown, genetic changes due factors such as environmental agents, immune response towards infectious agents influence rheumatoid arthritis. Earlier NSAIDs were first choice drugs for treatment b...

In this study, the purpose was to improve outdoor performance of cement bonded wood composite due their biodegradation and sensitivity moisture especially in warm humid climates. Cement composites were treated with different concentrations (10 %, 25 50 75 % 100 %) water repellent. Water repellent used an organo-silicon based, nano-sized, eco-friendly, water-based agents. Dipping pressure system...

1. Gramicidin caused H(+) production by liver mitochondria; this process was dependent on the presence of Na(+), Li(+), Rb(+) or Cs(+). In the presence of one of these alkali-metal ions and phosphate, gramicidin caused mitochondrial swelling and increased oxygen consumption. 2. Uncoupling agents, anaerobic conditions or respiratory inhibitors both inhibited and reversed H(+) production and swel...

Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis. Women, smokers, and those with a family history of the disease are most often affected. Criteria for diagnosis include having at least one joint with definite swelling that is not explained by another disease. The likelihood of a rheumatoid arthritis diagnosis increases with the number of small joints involved....

This study examined whether an aqueous solution that contained 18 organic chemicals that are either solvents or good swelling agents of PVC are able to cause softening when combined in a solution, with each solute at an activity of 0.05. This activity was selected because there is no evidence that an individual organic solute with an activity of 0.05 can soften PVC. However, we found that this ...

ATP can be released from a variety of cell types by mechanical stimulation; however, the mechanism for this release and the influence of pathology are not well understood. The present study examined intracellular signaling mechanisms involved in swelling-evoked (exposure to a hypotonic solution) release of ATP in urothelial cells from normal cats and cats diagnosed with interstitial cystitis (f...

A specific and potent inhibitor of S-adenosyl-L-homocysteine (AdoHcy) hydrolase, 9-[(1'R,2'S,3'R)-2', 3'-dihydroxycyclopentanyl]adenine (DHCaA), was evaluated for its immunosuppressive efficacy on murine T-cell proliferation in vitro and in several animal models, including delayed type hypersensitivity ear swelling and peptidoglycan polysaccharide-induced arthritis. The concanavalin A-induced [...