One year after resection of a parotid neoplasm, a 44-year-old man developed sweating over the left side of the face while eating (see video). He had to continuously dab his face with a cloth during a meal. He has been treated successfully with botulinum toxin. Gustatory sweating, known as Frey syndrome,1 results from misdirected regeneration of parasympathetic fibers normally innervating saliva...

In the year 1485 Henry Tudor landed at Milford Haven with an army of foreign mercenaries, and, marching to Boswortli Field, defeated Richard III. on August 22. He made his triumphant entry into London on August 27, and brought with him in his train "one by no means a captive." A deadly sickness broke out in the capital on September 19, so that more than fifteen thousand persons were cut off by ...

BACKGROUND Autonomic dysfunction, an early manifestation of diabetic neuropathy, presents with altered sweating patterns, leading to dryness and fissuring. We conducted a study to assess the sweat function in the diabetic foot and to determine the interrelation between the duration of diabetes, sensation, fissuring, and sweating. METHODS The sweat function was assessed in 30 diabetic patients...

BACKGROUND AND PURPOSE Sweating dysfunction is one of the most frequently encountered symptoms of autonomic failure but has received scant attention in patients with cerebrovascular diseases. Our purpose was to evaluate the prevalence, pathogenesis, and clinical correlates of sweating dysfunction in stroke. METHODS We studied sweating at baseline and after a heating stimulus in 53 patients wi...

We tested the hypothesis that clonidine produces a dose-dependent increase in the sweating threshold but does not reduce the gain of sweating. Six healthy male volunteers were evaluated, each on three separate days in random order. In one, saline was administered; in another, a 2-micrograms/kg bolus of clonidine was followed by an infusion at 2 micrograms.kg-1.h-1, and on a third day, a 4-micro...

A recent article in this journal describes an analysis of the 1551 outbreak of the sweating sickness.1 Dr Dyer's research, based on 680 extant parish registers, represents to date the most comprehensive and detailed analysis of the demographic impact of any of the five outbreaks of the sweating sickness of 1485, 1508, 1517, 1528 and 1551. Furthermore, his article supersedes previous analyses of...

Nitric oxide synthase (NOS) contributes to sweating and cutaneous vasodilation during exercise in younger adults. We hypothesized that endothelial NOS (eNOS) and neuronal NOS (nNOS) mediate NOS-dependent sweating, whereas eNOS induces NOS-dependent cutaneous vasodilation in younger adults exercising in the heat. Further, aging may upregulate inducible NOS (iNOS), which may attenuate sweating an...

Three cases of primary hyperhidrosis of no known cause, with excess sweating day and night, were treated using the same acupuncture points. The patients reported that their sweating decreased and that they felt better after the treatment.