We present the optimization of a new material structure used as transducer in a MagnetoOptical Surface Plasmon Resonance (MOSPR) biosensor. The MOSPR sensor is a modification of the standard Surface Plasmon Resonance (SPR) biosensor, which arises from the introduction of a ferromagnetic metal layer with Magneto-Optical (MO) activity together with the usual gold layer of SPR biosensors. Such com...

For a fiber optical surface plasmon resonance (SPR) sensor a short part of its cladding should be removed to coat a thin layer of a metal. Usually this is problematic when an optical fiber with small core diameter is used. In this paper, a new method using µliter droplet of the HF acid for short fiber optical taper fabrication is reported. Using this method in a multi-mode optical fiber w...

We present an integrated label-free biosensor based on surface plasmon resonance (SPR) and Faradaic electrochemical impedance spectroscopy (f-EIS) sensing modalities, for the simultaneous detection of biological analytes. Analyte detection is based on the angular spectroscopy of surface plasmon resonance and the extraction of charge transfer resistance values from reduction-oxidation reactions ...

We have experimentally confirmed sensitivity enhancement of a nanowire-based surface plasmon resonance (SPR) sensor structure. Gold nanowires with periods of 200 and 500 nm were fabricated, respectively, by electron-beam and interference lithography on a gold/SF10 substrate. Sensitivity enhancement was measured to be 44% compared with a conventional thin-film-based SPR structure for nanowires o...

The number and diversity of surface plasmon resonance (SPR) biosensor applications continue to increase. Evolutions in instrument and sensor chip technology, experimental methodology, and data analysis are making it possible to examine a wider variety of biomolecular interactions in greater mechanistic detail. SPR biosensors are poised to make a significant impact in basic research and pharmace...

Bimetallic islands films consisting of composite Au-Ag nanoparticles are deposited on glass substrates by electron beam evaporation. Broad tuning of the surface plasmon resonance (SPR) characteristics can be achieved by controlling film composition, deposition temperature and post-deposition thermal annealing. Optical and structural characterization of the samples enable to establish the link b...

The layer-by-layer processing of Au/Au(x)Pd(1-x) core/alloy nanoparticles via microwave irradiation (MWI) based hydrothermal heating is described. Alloy shell growth was monitored by the attenuation of surface plasmon resonance (SPR) as a function of shell thickness and composition. Discrete dipole approximation (DDA) correlated the SPR to particle morphology.

The recent work reporting the observation of the increase in sensitivity for surface plasmon resonance (SPR) spectroscopy at smaller incident angles, is further studied with variation in the temperature of the SPR sensor. Using a simple theoretical model established previously, it is found that in spite of the increase in damping for the resonance at higher temperatures, the recent finding of t...

Silver nanocubes (AgNCs), 60 nm, have four extinction surface plasmon resonance (SPR) peaks. The finite difference time domain (FDTD) simulation method is used to assign the absorption and scattering peaks and also to calculate the plasmon field intensity for AgNCs. Because AgNCs have a highly symmetric cubic shape, there is a uniform distribution of the plasmon field around them, and they are ...

The combination of surface plasmon resonance (SPR) and mass spectrometry (MS) creates a comprehensive protein investigation approach wherein SPR is employed for protein quantification and MS is utilized to structurally characterize the proteins. In such, MS utterly complements the SPR detection and reveals intrinsic protein structural modifications that go unregistered via the SPR detection. Pr...