The formation of imprinted memories during a critical period is crucial for vital behaviors, including filial attachment. Yet, little is known about the underlying molecular mechanisms. Using a combination of behavior, pharmacology, in vivo surface sensing of translation (SUnSET) and DiOlistic labeling we found that, translational control by the eukaryotic translation initiation factor 2 alpha ...

Molecular imprinting is a technique for preparing polymer scaffolds that function as synthetic receptors. Imprinted polymers that can selectively bind organic compounds have proven useful in sensor development. Although creating synthetic molecular-imprinting polymers that recognize proteins remains challenging, nanodevices and nanomaterials show promise in this area. Here, we show that arrays ...

Imprinting is a flexible and straightforward technique to generate selective sensor materials e.g. for mass-sensitive detection. Inherently, the strategy suits both molecular analytes and entire micro organisms or cells. Imprinted polyurethanes e.g. are capable of distinguishing the different xylene isomers with very appreciable selectivity factors. Combining imprinted titanates with surface tr...

a straightforward approach for the extraction of the quercetin was carried out by a nanoporous molecularly imprinted acrylic acid-based network copolymer as asolid sorbent. this technique involves a molecular template (quercetin) which is surrounded by functional monomers and are subsequently co-polymerized in the presence of an excess of the cross linkers. in this process, three-dimensional bi...

The unicellular Tetrahymena possess hormone receptors in the nuclear envelope similarly to higher rank animals. These receptors bind insulin and their specificity is detectable by monoclonal antibodies developed to insulin. The hormonal (insulin) pretreatment (imprinting) of the cell did not alter the binding capacity of the nuclear membrane, demonstrated by antibody-technique. The specific bin...

A novel technique for the creation of metal-organic framework (MOF) films based on soft-imprinting and their use as gas sensors was developed. The microporous MOF material [Zn₂(bpdc)₂(bpee)] (bpdc = 4,4'-biphenyldicarboxylate; bpee = 1,2-bipyridylethene) was synthesized solvothermally and activated by removing the occluded solvent molecules from its inner channels. MOF particles were characteri...

Surface imprinting used for protein recognition in functional cavities is highly effective biomacromolecules to avoid template encapsulation during the formation of a molecularly imprinted polymer (MIP) matrix. Herein, we introduce facile surface-imprinting method based on two-step spin-coating and photopolymerization design efficient sites polymeric films detect trypsin (TRY). Well-distributed...