Abstract The Wilms' tumor 1 (WT1) gene is well known as a chameleon gene. It plays role suppressor in but also acts an oncogene other cancers. Previously, our group reported that canonical AUG starting site for the WT1 protein (augWT1) suppressor, whereas CUG (cugWT1) functions oncogene. In this study, we report oncogenic of cugWT1 AOM/DSS-induced colon cancer mouse model and urethane-induced l...

background: many studies have been done in order to interpret correctly the results of ethanol analysis and its related problems. unfortunately, it was not easy to determine bac rate, due to postmortem different conditions or personal and clinical differences in metabolism and excretion of ethanol. the time between death and autopsy, the environmental conditions (temperature and humidity) are i...

To explore the function of curcumin on cartilage cells, cell proliferation and apoptosis by transforming growth factor-beta/suppressor mothers against decapentaplegic/a disintegrin metalloproteinase with thrombospondin motifs-7 axis was objective study. The viability detected counting kit-8. expression factor-beta, suppressor decapentaplegic protein, a motifs-7, caspase-9, B-cell lymphoma 2, Bc...

Purpose: To determine the influence of isoginkgetin on progression pulmonary carcinogenesis.
 Methods: A549 cells exposed to were transfected with miR-27a-5p mimetic and suppressor, as well short hairpin RNA against apurinic/apyrimidinic endo-deoxyribonuclease 1 (sh-APEX1) for 24 h. Then, proliferative, migration invasive potential determined using CCK-8, wound healing Transwell assays, re...

e-cadherin is among tumor suppressor genes which mostly subjects to the down-regulation in squamous cell carcinoma of esophagus (scce). the gene is tightly associated with the tumor invasion and metastasis in multiple human cancers, especially scce. cpg islands’ methylation in the promoter region of e-cadherin is among the mechanisms that have been suggested for the e-cadherin silencing, howeve...

OBJECTIVES The use of a suppressor tone has been proposed as the method of choice in obtaining single-generator distortion product (DP) grams, the speculation being that such DP grams will be more predictive of hearing thresholds. Current distortion product otoacoustic emissions (DPOAE) theory points to the ear canal DPOAE signal being a complex interaction between multiple components. The effe...