Random forest is a classification algorithm well suited for microarray data: it shows excellent performance even when most predictive variables are noise, can be used when the number of variables is much larger than the number of observations, and returns measures of variable importance. Thus, it is important to understand the performance of random forest with microarray data and its use for ge...

This paper presents a mathematical model for performing availability and reliability analysis of a parallel repairable system consisting of n identical components with degradation facility and common-cause failures. In addition, system repair time is assumed to be arbitrarily distributed. Markov and supplementary variable techniques are used to develop equations for the model. As an illustratio...

We consider an MMPP/G/1/K nite queue with twolevel threshold overload control. This model has frequently arisen in the design of the integrated communication systems which support a wide range applications having various Quality of Service (QoS) requirements. Through the supplementary variable method, we derive the queue length distribution.

We study an M/G/1 queue with two stages of heterogeneous service and single working vacation.Using supplementary variable approach we derive the probability generating function for the number of customers and the average number of customers in the system. Some special cases of interest are discussed. Mathematics Subject Classification: 60K25, 60K30

In M/G/1 retrial queueing system with two types of customers and feedback, we derived the joint generating function of the number of customers in two groups by using the supplementary variable method. It is shown that our results are consistent with those already known in the literature when δk = 0(k = 1, 2), λ1 = 0 or λ2 = 0.

Hydrogen-graphite interactions are relevant to a wide variety of applications, ranging from astrophysics to fusion devices and nano-electronics. In order to shed light on these interactions, atomistic simulation using Molecular Dynamics (MD) has been shown to be an invaluable tool. It suffers, however, from severe time-scale limitations. In this work we apply the recently developed Collective V...

Hydrocarbon Constrained Peptides – Understanding Preorganization and Binding Affinity Jennifer A. Miles, David J. Yeo, Philip Rowell, Silvia Rodriguez-Marin, Christopher M. Pask, Stuart L. Warriner, Thomas A. Edwards,* Andrew J. Wilson* School of Chemistry, Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, University of Leeds, Woodhouse Lane, Leeds LS2 9...

Chemical Space Guided Discovery of Antimicrobial Bridged Bicyclic Peptides Against Pseudomonas aeruginosa and its Biofilms Ivan Di Bonaventura, Xian Jin, Ricardo Visini, Daniel Probst, Sacha Javor, Bee-Ha Gan, Gaëlle Michaud, Antonino Natalello, Silvia Maria Doglia, Thilo Köhler, Christian van Delden, Achim Stocker, Tamis Darbre and Jean-Louis Reymond* Department of Chemistry and Biochemistry, ...