(figure). Capillary loops were not thickened and no trichrome positive deposits were seen. The tubules, interstitium, and blood vessels were all normal. Immunofluorescence studies were negative for all immunoglobulins, fibrin, and g-IC. Electron microscopy showed diffuse foot process fusion of the podocytes (see figure) with no electron dense deposits. The basement membrane was normal. He recei...

In standard crosses, some rIIB mutants of T4 phage were found to be susceptible to an extra recombination mechanism to which the other mutants were much less susceptible. The following observations were interpreted as evidence for the mismatch-repair nature of the phenomenon: (1) Marker-dependent recombination generates exclusively double exchanges at both sides of the marker. (2) Marker-depend...

Methylation of nuclear genes encoding mitochondrial proteins participates in the regulation of mitochondria function. The existence of cytosine methylation in the mitochondrial genome is debated. To investigate whether mitochondrial DNA (mtDNA) is methylated, we used both targeted- and whole mitochondrial genome bisulfite sequencing in cell lines and muscle tissue from mouse and human origin. W...

A standard task in pharmacogenomics research is identifying genes that may be involved in drug response variability, i.e., pharmacogenes. Because genomic experiments tended to generate many false positives, computational approaches based on the use of background knowledge have been proposed. Until now, those have used only molecular networks or the biomedical literature. Here we propose a novel...

We proposed a method that suggests subject headings based on user queries when a pattern-matching algorithm fails to locate subject searches for Online Public Access Catalogs (OPAC). We combined information obtained from Wikipedia, Amazon, and Google for query expansion. Our method has two main advantages: (1) availability for any library without customizing OPACs, and (2) ability to suggest su...

In interactive searching environments, robust linguistic techniques can provide sophisticated search assistance with a reasonable tolerance to errors, because users can easily select relevant items and dismiss the noisy bits. The general idea is that the combination of Language Engineering and Information Retrieval techniques can be used to suggest complex terms or relevant pieces of informatio...

Conflict is the most intriguing aspect of contact linguistics. Throughout history ever since the Tower of Babel was left unfinished, contacts between speakers of different languages have unavoidably resulted in conflicts between speakers of those languages. Without any doubt, the European Union (EU)--above all after the decision to enlarge the community--has accepted the multidisciplinary symbo...

In this paper we present a scheme to reduce the amount of user iterations required to segment an object by delineating on cross-section planes. Starting with an initial segmentation created from a small number of delineated curves, the algorithm progressively analyzes the uncertainty of segmentation with respect to the image features and suggests the “next plane” for delineation that would maxi...

Given a still image, humans can easily think of a sound associated with this image. For instance, people might associate the picture of a car with the sound of a car engine. In this paper we aim to retrieve sounds corresponding to a query image. To solve this challenging task, our approach exploits the correlation between the audio and visual modalities in video collections. A major difficulty ...

Sentence retrieval is an important NLP application for English as a Second Language (ESL) learners. ESL learners are familiar with web search engines, but generic web search results may not be adequate for composing documents in a specific domain. However, if we build our own search system specialized to a domain, it may be subject to the data sparseness problem. Recently proposed word2vec part...