AIMS The aim of this study was to investigate the interactive effect of physical training and chronic ethanol ingestion on changes in blood pressure (BP) and aortic reactivity response in rats. METHODS Male Fisher rats were divided into four groups of seven animals each and treated as follows: (i) control (5% sucrose, orally) daily for 12 weeks; (ii) ethanol (4 g kg(-1), orally) daily for 12 ...

BACKGROUND Jieyuanshen decoction (JYAS-D) - a traditional Chinese medicine was invented by Professor Nie based on classic formulas, chaihu jia longgu muli decoction has been proved as having favorable curative effects on depression in clinical practices. The aim of this study was to investigate the antidepressant effects and its molecular mechanism of JYAS-D. MATERIALS AND METHODS The model o...

In randomly bred rats, orally applied ethanol stimulates neural substrates for appetitive sweet taste. To study associations between ethanol's oral sensory characteristics and genetically mediated ethanol preference, we made electrophysiological recordings of oral responses (spike density) by taste-sensitive nucleus tractus solitarii neurons in anesthetized selectively bred ethanol-preferring (...

BACKGROUND Vaccine injections can cause acute pain and distress in infants, which can contribute to dissatisfaction with the vaccination experience and vaccine hesitancy. We sought to compare the effectiveness of additive pain interventions administered consistently during vaccine injections in the first year of life. METHODS We conducted a multicentre, longitudinal, double-blind, add-on, ran...

Background: Gentisic acid has been reported to show neuroprotective effect. But its effect on depression is not available in the literature. So we evaluated of this compound depressive behavior unstressed (normal) mice and stressed mice. Materials Methods: Swiss albino male were given unpredictable mild stressors for twenty-one consecutive days produce behavior. (25, 50, 100 mg/kg) fluoxetine (...

Controversy exists as toward the association of excessive fruits intake and certain disease risks. Longan is an edible fruit rich in high levels fructose, glucose sucrose. Herein, effect longan on development nonalcoholic fatty liver (NAFLD) was investigated. extracts at doses 4.0 g/kg, 8.0, 16.0 g/kg were orally administered for 4 weeks to healthy C57BL/6J mice or fed with a HFD diet. In norma...

background: cries of the newborn could be due to pain, thirst, hungry and fear from new environment. in our study we evaluated the effect of the sucrose drops on pacifying the children prior to a painful intervention or procedure with regards to the fasting condition of the children. methods: this triple blind clinical trial was conducted on 60 otherwise healthy children aged less than 1 year w...

the aim of this study was to establish and optimise a simplified method of halved grain culture, in order to utilise it to evaluate the ability of isolated sinks (developing wheat grains) in sucrose uptake and conversion (defined by sink strength) under unlimited source conditions. both sucrose uptake and starch synthesis increased linearly over the incubation periods used in this study. a ...

effect of different co2 concentrations on sucrose metabolizing enzymes and on carbohydrate metabolism was studied for eight blackgram (vigna mungo l. hepper) genotypes grown in open top chambers under ambient (380 µmol mol-1) vs. elevated co2 (550 and 700 µmol mol-1) levels. the higher acid invertase activity over neutral invertase indicated the major role of acid invertase in sucrose breakdown...