background: vanadium is an important environmental and industrial pollutant. it has a status of reproductive toxicant and is reported to cross placental barrier. objective: the current study was performed to assess the therapeutic efficacy of tiron and its combination with selenium against vanadium induced toxicity in lactating and suckling rats. materials and methods: rats were exposed to vana...

Noninfectious arbovirus antigens were prepared from borate-saline suspensions of infected suckling mouse brain buffered with tris(hydroxmethyl)aminomethane and treated with beta-propiolactone (BPL). The activity and stability of these antigens were enhanced by altering the buffering system, by passing the virus seed through a series of four or more continuous passages in the brains of suckling ...

Hitherto in poliomyelitis complement-fixation tests on human sera the antigenic material has usually been derived from tissue cultures of polio viruses. Despite high infectivity titres, antigens from this source are weak in capacity to fix complement (Selzer, 1958). Concentration of tissue culture antigens improves the complement-fixing power but frequently produces anti-complementary effects. ...

Exposure of Venezuelan equine encephalomyelitis (VEE) virus (at -70 C) to 6 x 106 r y-radiation (6WCo) resulted in loss of lethality for young adult mice and guinea pigs, and loss of capacity to produce plaques or cyLopathic effects in tissue culture. The suckling mouse was more sensitive for detecting live virus in radiated suspensions than was the adult mouse or guinea pig. Live virus was dem...

Tissue culture methods for the isolation and assay of the dengue viruses have been developed in a number of laboratories (1-7). Their aim has been to find an in vitro substitute for the suckling mouse (the usual host for these procedures). This study introduces a new method for the assay of mouse-adapted dengue viruses. Titrations and neutralization tests for serotypes 1, 2 and 4 have been cond...

In Préalpes de Sud ewes after an autumn lambing, the mean post-partum interval to first LH surge was 10 +/- 1 days and 17 +/- 1 days for non-suckling and suckling ewes, respectively. Post-partum interval to first luteal phase, estimated from plasma progesterone concentrations, was similar in non-suckling and suckling ewes (27 +/- 1 days and 28 +/- 5 days, respectively). Interval to first oestru...

Exposure of Venezuelan equine encephalomyelitis (VEE) virus (at -70 C) to 6 x 10 r gamma-radiation (Co) resulted in loss of lethality for young adult mice and guinea pigs, and loss of capacity to produce plaques or cytopathic effects in tissue culture. The suckling mouse was more sensitive for detecting live virus in radiated suspensions than was the adult mouse or guinea pig. Live virus was de...

Introduction. Recent experiments in this laboratory dis closed the fact that when ascites tumor cells were injected intraperitoneally into newborn or suckling mice, not only were tumor ascites and peritoneal tumor nodules produced generally, but tumors appeared in the lung at high rates, provided that injections were made within three or four days after birth. Organs other than the lung showed ...