The effect of plaque control on gingivitis and periodontitis is well-documented. In short-term investigations, chemical plaque control (oral rinsing twice a day with 0.2% chlorhexidine-gluconate solution) has been effective in the prevention of human gingivitis. Experimentally produced human gingivitis heals completely within one week when the same method is employed. Tooth cleaning with oral h...

The peripheral blood lymphocyte populations and the subgingival levels of black-pigmented Bacteroides species were monitored during the conversion of chronic gingivitis to progressing periodontitis in cynomolgus monkeys. In addition, the effects of an immunomodulating agent, the pentapeptide of thymopoietin (TP5), were determined. After the induction of active periodontitis, proportions of help...

The effect of gingival curettage facilitated by sodium hypochlorite solution on the subgingiva] micro flora of 21 juvenile periodontitis lesions was evaluated. Dark-field analysis and anaerobic culturing of juvenile periodontitis lesions were made immediately prior to treatment with gingival curettage facilitated by sodium hypochlorite solution-immediately after therapy, 30 days posttherapy, an...

OBJECTIVES The purpose of this study was to compare microbial profiles of saliva, pooled and site-specific subgingival samples in patients with periodontitis. We tested the hypotheses that saliva can be an alternative to pooled subgingival samples, when screening for presence of periopathogens. DESIGN Site specific subgingival plaque samples (n = 54), pooled subgingival plaque samples (n = 18...

Introduction: Periodontal disease results from a complex interplay between the subgingival biofilm and host immune-immflamatory events that develop in gingival periodontal response to challenge presented by bacteria. Gingivitis precedes periodontitis. In gingivitis , inflammatory lesion is confined gingiva, however, with periodontits, processes extend additionally affect ligament alveolar bone....