Supraphysiological ROS levels can lead to apoptosis, lipid peroxidation, and DNA protein damage. This pilot study aimed investigate the sperm oxidative damage in subfertile men, describe relationship between antioxidant system ROS. Sixty-four semen samples were categorised according evaluated routine parameters (WHO, WHO laboratory manual for examination processing of human semen, 2010). Result...

BACKGROUND Adverse reproductive performance has been linked to unhealthy dietary intake and lifestyles. Our objectives were to investigate the prevalence of unhealthy dietary intake and lifestyles before conception and to evaluate whether tailored preconception counselling modifies these behaviours. METHODS Between October 2007 and April 2009, 419 couples received tailored preconception dieta...

A practical approach to semen analysis (SA) interpretation and the initial management of subfertile men is presented. Each parameter of the SA is described and management recommendations based upon SA findings are provided. The indications for and interpretation of adjunctive diagnostic testing for male factor subfertility are also discussed.

OBJECTIVE To report the type and frequency of chromosomal anomalies and Y-microdeletions among Hong Kong Chinese subfertile men with sperm concentrations lower than 5 million/mL. DESIGN. Retrospective study. SETTING A reproductive centre in Hong Kong. PARTICIPANTS A total of 295 Chinese subfertile men who underwent both karyotyping and Y-microdeletion studies from 2000 to 2007 were categori...

The global health problems of infertility and sperm dysfunction In a world in which population growth and its subsequent control seem to be critical problems, it is counterintuitive to think that one in six couples are subfertile (still trying for a child after over 1 year of unprotected intercourse). In fact, approximately 80 million couples throughout the world are subfertile [1]. What is per...

OBJECTIVE To examine whether a relationship exists between loss of mitochondrial transmembrane potential and plasma membrane translocation of phosphatidylserine (PS) in subpopulations of human spermatozoa of men consulting for infertility. SETTING A tertiary institutional research center. DESIGN Prospective observational study. PATIENT(S) Twelve infertile men and five fertile controls wer...