The influence of chronic arterial hypertension upon the permeability to albumin of the cerebral capillaries, i.e. the blood-brain barrier, was studied in normotensive Wistar and spontaneously hypertensive Wistar rats with experimental subarachnoid hemorrhage. The blood-brain barrier permeability to albumin was assessed quantitatively by spectrophotometric determination of Evans blue extravasati...

AIMS To describe the anatomy and the arrangement of the arachnoid trabeculae, pillars, and septa in the subarachnoid space of the human optic nerve and to consider their possible clinical relevance for cerebrospinal fluid dynamics and fluid pressure in the subarachnoid space of the human optic nerve. METHODS Postmortem study with a total of 12 optic nerves harvested from nine subjects without...

In accordance with the trans-lamina cribrosa pressure difference theory, decreasing the trans-lamina cribrosa pressure difference can relieve glaucomatous optic neuropathy. Increased intracranial pressure can also reduce optic nerve damage in glaucoma patients, and a safe, effective and noninvasive way to achieve this is by increasing the intra-abdominal pressure. The purpose of this study was ...

Spinal arachnoid cysts generaiiy communicate with the subarachnoid space. Theyare considered as benign entities and are rarely seen in neurosurgical practice (2, 9-11). Presentation with cornpressian of the spinal cord andi or roots may sametimes occur and this may be symptomatic, as myelopathy andi or radiculopathy (1-12). In this paper a case of intradural arachnoid cyst in the midthoracic re...

A case is reported of an uneventful continuous extradural block in spite of unrecognized dural perforation. Although the perforation was recognized later during the block, the dura was probably pierced during the insertion of the catheter and only later the terminal hole came to lie in the subarachnoid space. Consequently both extradural and subarachnoid spread of the injected local anaesthetic...

BACKGROUND AND PURPOSE How CSF flow varies with the anatomy of the subarachnoid space has not been sufficiently well studied. The goal of this study was to develop an idealized 3D computational model of the subarachnoid space and then to use this model to study the detailed spatiotemporal effects of anatomic variations on CSF pressures and velocities. MATERIALS AND METHODS We created a geomet...

OBJECT The pathogenesis of syringomyelia in patients with an associated spinal lesion is incompletely understood. The authors hypothesized that in primary spinal syringomyelia, a subarachnoid block effectively shortens the length of the spinal subarachnoid space (SAS), reducing compliance and the ability of the spinal theca to dampen the subarachnoid CSF pressure waves produced by brain expansi...

Spinal extradural meningeal cyst has been rarely reported, whose etiologies are assumed to be the communication of cerebrospinal fluid (CSF) between intradural subarachnoid space and cyst due to the congenital defect in dura mater. Although the CSF communication due to this defect can be found in most case, few cases in which there is a lack of the communication have also been reported. We repo...

Seventeen cases are reported in which fatal subarachnoid haemorrhage was associated with injury to the upper cervical region. Most of these cases were alcohol-intoxicated, most had sustained their injuries in an altercation, and death was usually but not invariably rapid. It is proposed that trauma to the upper cervical region can cause subarachnoid haemorrhage, by a mechanism involving trackin...