Penile erection is a neurovascular phenomenon, and erectile dysfunction (ED) is caused mainly by vascular risk factors or diseases, neurologic abnormalities, and hormonal disturbances. Men with diabetic ED often have severe endothelial dysfunction and peripheral nerve damage, which result in poor response to oral phosphodiesterase-5 inhibitors. Nerve injury-induced protein 1 (Ninjurin 1, Ninj 1...

Comprehensive research to quantify the deformability of erythrocytes in diabetic animals and humans has been lacking. The objective of this study was to compare the impairment of erythrocyte deformability in diabetic rats and patients by use of the same rheologic method. Deformability was investigated in streptozotocininduced diabetic rats and diabetic patients, by using the highly sensitive an...

This study aimed to assess the protective potential of glimepiride and Nerium oleander extract on lipid profile, body growth rate, and renal function in streptozotocin-induced diabetic rats. The animals were divided into control and experimental groups. The experimental group was rendered diabetic by intraperitoneal injection of a single dose of 50 mg/kg body weight streptozotocin. Rats with gl...

OBJECTIVE Silver plays an important part in severe wound management, mainly by reducing microbial growth within dressed wounds and wound beds. However, it is unknown how silver-coated dressing materials affect diabetic wounds. The purpose of this study is to evaluate the efficacy of silver-containing dressing materials for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-infe...

Panax ginseng has long been used as a traditional herbal medicine. More recently, it has received attention for its anti-diabetic and anti-obesity effects in humans and in animal models of type 2 diabetes. In the present study, we tested the hypoglycemic effects of ginseng berry extract in beta-cell-deficient mice and investigated the mechanisms involved. Red (ripe) and green (unripe) berry ext...

background: considering the effect of socioeconomic factors on the appearance of chronic diseases, and also the importance of this issue for policy makers of health care services, we tried to assess the role socioeconomic factors have in diabetes complications. this survey may have some benefits in prevention and control of diabetes.   methods: this cross-sectional study was conducted on 384 di...

abstract objective: diabetic peripheral neuropathy is the main risk factor of diabetic foot ulcer and its early diagnosis is important to prevent limb amputation. we assessed the prevalence of peripheral neuropathy in diabetic patients. materials and methods: this cross-sectional study was performed on 352 randomly selected diabetic patients using a standardized questionnaire including age, gen...

background: diabetes has a high prevalence in iran and it is estimated to rise from 3.5 million adults in 2005 to 5.1 million by 2025. given the high prevalence of diabetes in iranians, it is surprising how little is known about understanding of diabetes in public population. this study aimed to explore and describe people without diabetes explanation for the disease. materials and methods: thi...