This report describes a simple method for the isolation of streptomycin-dependent tubercle bacilli from virulent cultures that have not previously been exposed to streptomycin. The in vivo isolation of streptomycin-dependent Mycobacterium tuberculosis has been reported by Spendlove et al. (1948) and Lenert and Hobby (1949). The in vitro procedure described here is applicable to the quantitative...

Penicillin-streptomycin, bacitracin methylene disalicylate, zinc bacitracinm, soluble bacitracin methylene disalicylate, streptomycin (25%) and spectinomycin were used as prophylactic and therapeutic treatments for ulcerative enteritis in bobwhite quail (Colinus virginianus). Penicillin-streptomycin was the most effective prophylactic and streptomycin (25%) was the most effective therapeutic ag...

Hurwitz, Charles (Veterans Administration Hospital, Albany, N.Y.), and Carmen L. Rosano. Evidence for a streptomycin permease. J. Bacteriol. 90:1233-1237. 1965.-The hypothesis that an induced streptomycin permease is required for entry of the antibiotic into cells is further supported by the finding that proflavine and borate, which inhibit transcription, also block the lethal action of strepto...

introduction: streptomyces species are mycelial, aerobic gram-positive bacteria that are isolated from soil and produce a diverse range of antibiotics. streptomyces griseus produces the antibiotic, streptomycin and forms spores even in a liquid culture. the gene cluster for the production of streptomycin antibiotic contains strr gene that encodes strr, a pathway-specific regulator. then, this p...