The desert, which covers around one-third of Earth’s continental surface, is defined as the harshest terrestrial environment and comprises a highly extensive biome ecosystem. Microorganisms are key drivers that maintain integrity desert ecosystems. Over past few decades, desertification has increased owing to changes in rainfall patterns global warming, characterized by land degradation, loss m...

The field of bacterial natural product research is currently undergoing a paradigm change concerning the discovery of natural products. Previously most efforts were based on isolation of the most abundant compound in an extract, or on tracking bioactivity. However, traditional activity-guided approaches are limited by the available test panels and frequently lead to the rediscovery of already k...

Miksobakteriler pek çok antibakteriyel, antifungal, antikanser, antiparazit, immunosupresif, sitotoksik ve antioksidatif biyoaktif bileşiklerin önemli kaynağı kabul edilmektedir. Antibiyotiğe dirençli patojen bakterilerin neden olduğu hastalıkların artmasıyla birlikte, doğal kaynaklardan bu patojenlerin kontrol edilmesi/yok edilmesini sağlayacak daha etkili yeni antibiyotiklere ihtiyaç duyulmak...

Stigmatella aurantiaca is a gram-negative bacterium which forms, under conditions of starvation in a multicellular process, characteristic three-dimensional structures: the fruiting bodies. For studying this complex process, mutants impaired in fruiting body formation have been induced by transposon insertion with a Tn5-derived transposon. The gene affected (fbfB) in one of the mutants (AP182) ...