The integration of different existing tools, each of them not covering the whole life cycle, to a SEE (Software Engineering Environment) is an actual task. There are two main mechanisms of integration. The fIrst one is the vertical integration, that means, that a common user interface and a common data base are available for the tools to be assembled into a CASE Environment. ( The second one is...

BACKGROUND We investigated very long-term bowel function after total mesorectal excision (TME) with or without preoperative short-course radiotherapy (PRT) for rectal cancer, the risk factors for bowel dysfunction, and the association of bowel dysfunction with health-related quality of life (HRQL). PATIENTS AND METHODS In the TME trial (1996-1999), 1530 Dutch patients with rectal cancer were ...

Objective: The aim of this study was to develop and validate a scoring system for bowel dysfunction after low anterior resection (LAR) for rectal cancer, on the basis of symptoms and impact on quality of life (QoL). Background: LAR for rectal cancer often results in severe bowel dysfunction (LAR syndrome [LARS]) with incontinence, urgency, and frequent bowel movements. Several studies have inve...

OBJECTIVE The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and cli...

Another post with Dynamics And Bifurcation Of Patterns In Dissipative Systems : dynamics and bifurcation of patterns in dissipative systems dynamics and bifurcation of patterns in dissipative systems dynamics and bifurcation of patterns in dissipative systems bifurcation and stability of dissipative systems nbwzy dynamics and bifurcation of patterns in dissipative systems dynamics and bifurcati...

OBJECTIVE The aim of this study was to develop and validate a scoring system for bowel dysfunction after low anterior resection (LAR) for rectal cancer, on the basis of symptoms and impact on quality of life (QoL). BACKGROUND LAR for rectal cancer often results in severe bowel dysfunction (LAR syndrome [LARS]) with incontinence, urgency, and frequent bowel movements. Several studies have inve...

In numerical dosimetry, the recent advances in high performance computing led to a strong reduction of the required computational time to assess the specific absorption rate (SAR) characterizing the human exposure to electromagnetic waves. However, this procedure remains time-consuming and a single simulation can request several hours. As a consequence, the influence of uncertain input paramete...

We consider the problem of selecting grouped variables (factors) for accurate prediction in regression. Such a problem arises naturally in many practical situations with the multi-factor ANOVA problem as the most important and well known example. Instead of selecting factors by stepwise backward elimination, we focus on estimation accuracy and consider extensions of the LASSO, the LARS, and the...