Introduction: The present study was conducted to evaluate the effect of Chlorogenic Acid (CA) and Diazepam (DZP) on epileptic complication that induced by repetitive intra-peritoneal injections of Pentylenetetrazle (PTZ) in aged rats.   Methods: Twenty-four month-old male Wistar rats (age > 12 months, 300-350 g) were divided in 4 experimental groups. Animal in control group (PTZ + Vehicle) re...

BACKGROUND The interest of low molecular weight heparins (LMWH) regarding bleeding risk is controversial in renal failure patients. In haemodialysis patients, there are very few data on the pharmacokinetics of LMWH after the end of the session. The aim of the study was to evaluate the duration of anticoagulation after bolus administration of the LMWH enoxaparin at the start of haemodialysis. ...

The aim of this study was to compare the therapeutic effects of rhGH administered either by subcutaneous needle-injection (pens) or subcutaneous needle-free jet-injection (VISION(®)). Furthermore, a survey was carried out after using VISION(®) for 12 mo. A needle-free injection group consisting of 18 subjects (11 males and 7 females, mean age 5.87 ± 2.05 yr at the start of hGH therapy) who have...

Hypercapnic blood was injected into the vertebral artery in anesthetized and paralyzed cats. The stimulating effect on the phrenic nerve activity was dependent on the injection rate, duration, and PCO2 level of the injected blood. The time delay from the start of injection to the onset of increase in phrenic nerve activity was inversely proportional to both the injection rate and the PCO2 of in...

Abbreviations: aBDC, after bottomdead center; aTDC, aft bottomdead center; bTDC, before top dead center; CA50, cra fraction reaches to 50%; CI, compression ignition; COVime indicated mean effective pressure; DI, direct injection; DIS DOI, duration of injection (first DOI1, second DOI2); EGR, homogenous charge compression ignition; IMEP, indicat injection ratio; MPRR, maximum pressure rise rate;...

A new approach is outlined in which group modeling techniques are used to model an individual user. This helps to reduce cold-start problems, and allows aggregating multiple criteria.