Incubation of a 0.5% suspension of washed, normal mouse erythrocytes with ferriprotoporphyrin IX (FP) at 37 degrees C and pH 7.4 caused potassium loss, swelling, increased susceptibility to hypotonic lysis, and finally hemolysis. Hemolysis was not inhibited by incubation in the dark, malonyldialdehyde was not produced, and various free radical scavengers had no effect on the hemolysis. Only the...

By A. SZEINBERG, CH. SHEBA AND A. ADAM W E EMBARKED ON THE STUDY of hematologic differences between Ashkenazic and non-Ashkenazic Jews#{176}when it was certain that only the latter were victims of hemolysis due to known (Vicia faba, sulpha drugs) or unknown (bacterial, viral?) noxious agents. We assumed the existence of a familial inherited trait of the red blood corpuscle, in addition to which...

Results. In order to study the hemolytic activity of Streptococcus, α -, β - and γ -isolated from samples clinical material synanthropic birds rodents, we studied 324 cultures Streptococcus. rats, mice caught in livestock buildings -types hemolysis were mainly manifested, -hemolysis was observed less frequently. To properties 140 Streptococcus isolated air, washings walls floors, as well feeder...

The oxidative hemolysis of rabbit erythrocytes induced by free radicals and its inhibition by chain-breaking antioxidants have been studied. The free radicals were generated from either a water-soluble or a lipid-soluble azo compound which, upon its thermal decomposition, gave carbon radicals that reacted with oxygen immediately to give peroxyl radicals. The radicals generated in the aqueous ph...

To evaluate the occurrence of hemolysis during double-filtration plasmapheresis (DFP) treatment and its causes, we prospectively treated 113 myasthenic patients and monitored transmembrane pressure (TMP), arterial line pressure (Pa), and venous line pressure (Pv) at 30-minute intervals (M30, M60, M90, and M120) during treatment. Laboratory and clinical parameters related to the development of h...

Sixty-two patients were investigated for chronic intravascular hemolysis from 3 months to 6iS years following aortic valve replacement; 27 patients had Starr-Edwards prostheses and 35 fascia lata grafts. The findings are suggestive of a significantly higher incidence and degree of hemolysis in patients with Starr-Edwards prostheses compared to those with fascia lata grafts. In both groups regur...

The effect of osmotic protectors (sucrose and polyethylene glycols) and of a decrease in the detergent concentration at different points of hemolysis of human erythrocytes by sodium dodecyl sulphate on the shape of kinetic curves of hemolysis were studied. It is shown that slow detergent-induced hemolysis follows the colloid-osmotic mechanisms. Evidence is provided that rapid hemolysis by sodiu...

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in human. The aim of this study was to determine the prevalence of G6PD deficiency among children and evaluate its association with ABO/Rh blood groups. Method: Blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemolys...

Hemolysis presents as acute or chronic anemia, reticulocytosis, or jaundice. The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings. Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hered...

seizure is a rare presentation for acute hemolysis due to g6pd deficiency. we report a previously healthy boy who presented initially with seizure and cyanosis and subsequently acute hemolysis, due to glucose-6-phosphate dehydrogenase deficiency (g6pd) and probably secondary methemoglobinemia, following the ingestion of fava beans.