This article aims to summarize the current state of knowledge on St. John's wort (Hypericum perforatum L.) which is one of the oldest and best investigated medicinal herbs. Dried alcoholic extracts are the most important preparations on the market although a variety of other preparations are available. Depressive disorders according to modern diagnostic standards are the best known and most wid...

Depression is a common and serious mood disorder, with nearly 7% of U.S. adults reporting at least one episode major depression in the past year. The adverse effects associated antidepressants cause many patients to turn alternative treatments like St. John's wort (Hypericum perforatum). This yellow-flowering plant most popular supplements promoted for depression, menopause symptoms, disorders....

An extract of the herb St. John’s wort was no more effective for treating major depression of moderate severity than placebo, according to research published in the April 10 issue of the Journal of the American Medical Association. The randomized, double-blind trial compared the use of a standardized extract of St. John’s wort (Hypericum perforatum) to a placebo for treating major depression of...

BACKGROUND Extracts of the plant Hypericum perforatum L. (popularly called St. John's wort) have been used in folk medicine for a long time for a range of indications including depressive disorders. OBJECTIVES To investigate whether extracts of hypericum are more effective than placebo and as effective as standard antidepressants in the treatment of depressive disorders in adults; and whether...

The first in vitro study of seed dormancy breakage Iranian populations St. John’s Wort (Hypericum perforatum) with different geographical origins

Athletes regularly combine maximal strength, power, and hypertrophy-oriented training within the same workout. Traditionally, it has been suggested that power-oriented exercises precede strength and hypertrophy-oriented training within a workout to avoid the possible negative effects that the latter types of training may have on power output. However, with regard to upper-body training, little ...

We present preliminary results of B K calculated using improved staggered fermions with the mixed action (valence quarks = HYP staggered fermions and sea quarks = AsqTad staggered fermions). We analyze the data based upon the prediction by Van de Water and Sharpe. A hint of consistency with the prediction is observed. We also present preliminary results of B ¡ 3¢ 2£ 8 and B ¡ 3¢ 2£ 7 .

Our context is the study of ω-models of subsystems of second order arithmetic [5, Chapter VIII]. As in [5, Chapter VII], a β-model is an ω-model M such that, for all Σ1 sentences φ with parameters from M , φ is true if and only if M |= φ. Theorems 1.1 and 1.3 below are an interesting supplement to the results on β-models which have been presented in Simpson [5, §§VII.2 and VIII.6]. Let HYP deno...

BACKGROUND Monoamine oxidase A (MAO-A) inhibitor antidepressants raise levels of multiple monoamines, whereas the selective serotonin reuptake inhibitors (SSRIs) only raise extracellular serotonin. Despite this advantage of MAO-A inhibitors, there is much less frequent development of MAO inhibitors compared with SSRIs. We sought to measure brain MAO-A occupancy after 6 weeks of treatment in dep...